Carcinoma, Hepatocellular Clinical Trial
Official title:
A Randomized Controlled Trial of Ethanol-gelfoam Mixture(EGM) Versus Gelfoam for the Treatment of Arterioportal Shunts (APS) in Patients With Hepatocellular Carcinoma (HCC) Treated With Transarterial Chemoembolization (TACE)
Transcatheter arterial chemoembolization (TACE) is a key palliative treatment for patients
with inoperable hepatocellular carcinoma (HCC). Arterioportal shunts (APS) can aggravate
portal hypertension and the shunts let lipiodol flow to normal liver tissue and result in
poor Lipiodol deposition in the tumor, causing liver ischemia.
Occlusion of APS is a vital and initial step for the following embolization of tumor.
Ethanol-gelfoam mixture(EGM) and gelfoam only both can occlude APS in patients with
hepatocellular carcinoma (HCC).
The aim of this study was to evaluate the efficacy and safety of EGM in treatment of APS in
the procedure of TACE, and to analyze the prognostic factors for survival in this kind of
patients.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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