Safety Study of Foretinib (GSK1363089) in Adults With Liver Cancer

Status Completed

Clinical Trial Summary

The purpose of this study is to assess the safety and tolerability of foretinib (also known as GSK1363089) when used in the treatment of patients with advanced hepatocellular carcinoma (liver cancer).

Clinical Trial Description

The purpose of this study is to identify the maximum tolerated dose (MTD) of foretinib (also known as GSK1363089) when used in the treatment of patients with advanced hepatocellular carcinoma (liver cancer), and to assess the safety and tolerability of that dose in this patient population.

The MTD will be identified during Phase I, by standard dose-escalation of foretinib. Then Phase II will assess the safety and tolerability of foretinib dosed at MTD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00920192
Study type	Interventional
Source	GlaxoSmithKline
Contact
Status	Completed
Phase	Phase 1
Start date	August 12, 2009
Completion date	March 24, 2015

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