Carbon Monoxide Poisoning Clinical Trial
— CO-OXOfficial title:
Role of Pulse Co-oximetry in Prehospital Emergency Medical Service Management of Suspected Carbon Monoxide Poisoning : A Prospective Multicenter Study.
The RAD-57 pulse CO-oximeter is a lightweight device allowing non-invasive measurement of
blood carboxyhemoglobin. Previous studies comparing RAD-57 measurements (SpCO) to standard
laboratory blood gas analysis (COHb) have reported contradictory results.
the RAD-57 pulse CO-oximeter could be useful as a first-line screening test for acute CO
poisoning, enabling rapid detection and management of patients with suspected CO poisoning
in the prehospital emergency setting This study assesses the diagnostic value of pulse
CO-oximetry, comparing SpCO to standard laboratory blood measurement for prehospital
management of patients with suspected carbon monoxide (CO) poisoning.
Status | Recruiting |
Enrollment | 176 |
Est. completion date | December 2017 |
Est. primary completion date | December 2017 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion criteria: - Patient aged 18 years or older - Patient managed by prehospital emergency medical services. - Patient with a suspected CO exposure presenting or not with clinical signs of CO poisoning Exclusion criteria: - Patient for whom venous blood sampling cannot be obtained prehospitally - Patient for whom SpCo measurement cannot be performed prehospitally (cardiac arrest, peripheral vasoconstriction) |
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Country | Name | City | State |
---|---|---|---|
France | Montpellier University hospital - Emergency department | Montpellier |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Montpellier | french society for emergency medicine |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | SpCO optimal threshold value for detection of CO poisoning | prehospital medical management | Baseline | No |
Secondary | SpCO level | prehospital medical management | Baseline | No |
Secondary | COHb Blood carboxyhemoglobin level | prehospital medical management | Baseline | No |
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