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Capsule Opacification clinical trials

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NCT ID: NCT05001932 Recruiting - Cataract Clinical Trials

Optimizing Refractive Results and Patient Satisfaction After Cataract Surgery

ORAPSCA
Start date: August 11, 2021
Phase: N/A
Study type: Interventional

Cataract surgery is the most common eye surgery in the world. If the patient with cataract uses spectacles and both patient and surgeon find it beneficial, it is possible to compensate for the spectacles during surgery and thereby obtain a spectacle-free distance vision or spectacle-free near vision. Becoming spectacle free increases quality of life substantially and is one of the primary wishes in cataract patients. Socioeconomically, spectacle free life is beneficial as it reduces fall tendency in the elderly population. Multifocal lenses warrant the possibility of obtaining a spectacle free vision at near, intermediate and distance. It is also possible to obtain spectacle free distance and near vision or distance and intermediate vision by using traditional artificial monofocal lenses but making one eye spectacle free for distance and the other eye spectacle free for near or intermediate vision. Currently, it is not know which procedure is most beneficial for cataract patients. In a recent PhD, the investigators developed a method, Aniseikonia Tolerance Range (ATR), that can assess how much refractive change a patient can endure without impairing stereopsis. The results demonstrated large variation in the tolerance of image difference. This method can be a future tool to assess whether a patient can tolerate the refraction that is considered most beneficial to the patient. The knowledge is important as it can help avoid improper lens choice in cataract surgery and thereby avoid stereopsis problems.

NCT ID: NCT04952987 Recruiting - Dry Eye Clinical Trials

Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery

Start date: January 1, 2021
Phase:
Study type: Observational

The objective of this study is to evaluate the efficacy of Diquafosol 3% in the management of dry eyes before and after cataract surgery. Patients with pre-existing dry eyes and planned for cataract surgery will be started on Diquafosol eyedrops prior to surgery and treatment will be continued after cataract surgery. Eligible patients will undergo evaluation of dry eye at baseline and subsequently started on treatment with Diquafosol for the duration of 4 weeks before surgery. Further evaluations will be conducted on the day of surgery and at designated time points during and up to 12 weeks after surgery.

NCT ID: NCT04882189 Recruiting - Clinical trials for Endothelial Cell Density Loss

Study of Endothelial Cell Condition After Cataract Surgery Performed Using Capsulorhexis or ZEPTO

ZEPTO
Start date: August 23, 2021
Phase:
Study type: Observational

This study will use images of the subjects' corneal endothelium obtained using non-invasive specular microscopy to obtain corneal endothelial cell density, the coefficient of variation in endothelial cell size, and the percentage of hexagonal endothelial cells following routine cataract surgery performed using the standard method of manual capsulorhexis compared to cataract surgery performed using Zepto Precision Capsulotomy System.

NCT ID: NCT04776057 Recruiting - Astigmatism Clinical Trials

Rotation Stability of Toric Intraocularlens (IOL) Compared Sitting Against Lying After Cataract Operation

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

To assess the rotation stability of toric intraocular lenses between sitting or routine settings (sitting, going around) after cataract operation.

NCT ID: NCT04759560 Recruiting - Congenital Cataract Clinical Trials

Biometric Characteristics of the Eye With Microcornea/Microphthalmia and Congenital Cataract Before And After Cataract Extraction

Start date: July 25, 2020
Phase:
Study type: Observational

Early cataract surgery in microcornea/microphthalmia eyes is essential to prevent amblyopia and improve visual outcomes, including stereopsis. However, despite recent advances in pediatric cataract microsurgical techniques, this surgery remains challenging owing to several intraoperative difficulties attributable to the crowded anterior segment in these small, soft, and poorly developed eyes with shallow anterior chambers, and poor pupillary dilation. In this study the investigator aim to report on the changes in the anterior segment biometric characteristics after cataract extraction in eyes with microcornea/microphthalmia with congenital cataract.

NCT ID: NCT04161963 Recruiting - Cataract Clinical Trials

Incidence of Sub-clinical Cystoid Macular Edema After Cataract Surgery

ICCME
Start date: March 4, 2019
Phase:
Study type: Observational

Cystoid macular edema (CME) can limit visual acuity after cataract surgery. Little is known whether the incidence is similar between standard ultrasound phacoemulsification cataract surgery (phaco), femtolaser assisted cataract surgery (FLACS), and combined phacoemulsification cataract surgery plus micro invasive glaucoma surgery (phaco+MIGS) procedures.

NCT ID: NCT04050644 Recruiting - Clinical trials for Age-related Cataract

Comparison of Treatment With Preservative-free Dexamethasone 0.1% (Monofree Dexamethason) and Diclofenac 0.1% (Dicloabak) Eye Drops Versus Preserved Dexamethasone 0.1% (Maxidex) and Diclofenac 0.1% (Voltaren Ophtha) Eye Drops After Cataract Surgery

GIST
Start date: October 30, 2018
Phase: Phase 4
Study type: Interventional

To compare treatment with preservative-free dexamethasone 0.1% (Monofree Dexamethason) and diclofenac 0.1% (Dicloabak) eye drops versus preserved dexamethasone 0.1% (Maxidex) and diclofenac 0.1% (Voltaren Ophtha) eye drops after cataract surgery in terms of postoperative inflammation, iatrogenic dry eye disease and cystoid macular edema.

NCT ID: NCT03857685 Recruiting - Clinical trials for Posterior Capsule Opacification

LEC Proliferation in Vivo and In-vitro

Start date: January 1, 2019
Phase:
Study type: Observational

Investigate the proliferative capacity of individual lens epithelium capsule specimens in vitro and correlate it to the risk of developing PCO

NCT ID: NCT03857412 Recruiting - Clinical trials for Posterior Capsule Opacification

Posterior Capsule Opacification After Lens Capsule Polishing

Start date: February 13, 2019
Phase: N/A
Study type: Interventional

Investigate the effect of polishing of the lens capsule during cataract surgery on the development of posterior capsule opacification

NCT ID: NCT03701139 Recruiting - Cataract Clinical Trials

Posterior Capsulotomy in Cataract Complicated With Primary Posterior Capsule Opacification.

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

This is a two-arm, parallel group, open-label, randomized controlled trial to compare the visual acuity, visual quality, operative complications and the satisfaction of patients between primary posterior capsulorhexis group and laser capsulotomy group of cataract patients combined with primary posterior capsular opacification (PPCO).