Detection of Cannabis Impairment With ISBRG's SpotLight-THC

Status Recruiting

Clinical Trial Summary

Subjects will participate in a 2-visit study protocol in which they will be administered cannabis of pre-determined concentrations and asked to complete a simulated drive in a driving simulator. Subjects will be scanned on two SpotLight-THC (Alpha and Beta iterations) devices and peripheral venous whole blood will be collected from subjects for analysis on up to four occasions on each visit. The purpose of the investigation will be to determine whether the SpotLight-THC device is a reliable measure of THC impairment at the roadside, with an objective to identify a unique blood analyte architecture for THC impairment using near infrared light and machine learning.

Clinical Trial Description

At the University of Iowa, subjects who currently use cannabis recreationally will be recruited. They will then undergo a screening visit in which consent is obtained, questionnaires are given, a physical exam is conducted and subjects will use the driving simulator to assess propensity to sickness and to familiarize them with the simulation. They will then be scheduled for their next visit. At the second visit, subjects will be administered 5-10% THC. A series of baseline tests, including a test requiring a blood sample will be administered upon arrival. After drug administration, subjects will be asked to complete a set of verbal recall questions followed by three simulated driving trials, completing 7 non-invasive SpotLight-19 scans (20 seconds x 2) and 3 blood samples throughout the visit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05276232
Study type	Interventional
Source	ISBRG Corp
Contact	Rose A Schmitt, B.S.
Phone	319-335-4666
Email	rose-potter@uiowa.edu
Status	Recruiting
Phase	Phase 1
Start date	March 2022
Completion date	August 2022

View Details

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