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Clinical Trial Summary

This study is to assess the MTD and RP2D of NM6603 in adult patients with advanced solid tumors.


Clinical Trial Description

This is a Phase 1, first-in-human, multicenter, open label, 3+3 dose escalation study designed to evaluate the safety profile, the maximum tolerated dose (MTD), the recommended Phase 2 dose (RP2D), the pharmacokinetic and the preliminary antitumor activity of NM6603 in patients with advanced solid tumors. The study has two parts. In Part 1, NM6603 will be administered once daily. In Part 2, NM6603 will be administered twice daily to explore the effect of twice daily dosing on the pharmacokinetic, safety and tolerability, and anti-tumor activity profile of NM6603, ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06046066
Study type Interventional
Source NucMito Pharmaceuticals Co. Ltd.
Contact COO
Phone +86-15306980619
Email ClinicalDevelopment@nucmito.com
Status Recruiting
Phase Phase 1
Start date August 31, 2023
Completion date July 31, 2026

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