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TaxXel: Taxotere and Xeloda in Esophageal Cancer — TaxXel  

Cancer of the Esophagus Clinical Trial

Official title:
A Phase I/II Study on the Treatment With Taxotere in Combination With Xeloda in Patients With Metastatic Oesophageal Cancer or Cancer in the Cardia Region

Clinical Trial Summary

This is an open label, non-randomised, multicentre phase 1-2 study with a fixed dose of Taxotere in combination with Xeloda which is dose escalated during the first phase of the study (modified Fibonacci design) and fixed during the second phase.

The primary objective of the phase 1 part is to define the dose recommended for the Phase II part of the study. The primary objective is to determine the response rate.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00821912
Study type Interventional
Source Karolinska University Hospital
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date March 2006
Completion date September 2013
View Details
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