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C.Surgical Procedure; Cardiac clinical trials

View clinical trials related to C.Surgical Procedure; Cardiac.

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NCT ID: NCT01998438 Completed - Clinical trials for C.Surgical Procedure; Cardiac

Prospective Trial of Tranexamic Acid in Cardiac Surgery

Start date: September 2012
Phase: Phase 4
Study type: Interventional

Tranexamic acid, an antifibrinolytic drug, is wildly used in cardiac surgeries to decrease perioperative bleeding and allogenic transfusion. But the optimum dose of tranexamic acid is still unknown. We use three different doses to find which is the optimum dose of tranexamic acid in cardiopulmonary bypass cardiac surgery.

NCT ID: NCT01805466 Completed - Clinical trials for C.Surgical Procedure; Cardiac

Effects on Organ Damage and Surgical Outcome of a New Cardiopulmonary Pass System (EVADO)

EVADO
Start date: October 2012
Phase: N/A
Study type: Interventional

The primary purpose of this study is to assess the effects of the use of EVADO with respect to a conventional cardio-pulmonary bypass (CBP) system on surgical morbidity and mortality. As secondary aim this study wants to conduct appropriate laboratory investigations in order to detect the major biological mechanisms potentially responsible for the beneficial effects of the EVADO system on the coagulation cascade and inflammatory activation.

NCT ID: NCT00598195 Completed - Clinical trials for C.Surgical Procedure; Cardiac

Ketamine Pharmacokinetics in Children Having Heart Surgery

Start date: June 2006
Phase: N/A
Study type: Interventional

What are the pharmacokinetics of ketamine in infants and children requiring ketamine for induction of anesthesia for cardiac surgery that requires CPB? Specific Aim 1: To determine the pharmacokinetic parameters of a single intravenous bolus dose of ketamine in infants and children undergoing cardiac surgery with and without CPB (cardio-pulmonary bypass). Specific Aim 2: To describe the disposition of ketamine's primary active metabolite, norketamine,following a single intravenous bolus dose of ketamine in infants and children undergoing cardiac surgery with and without CPB. Specific Aim 3: To determine the relationship between ketamine and norketamine pharmacokinetic parameters and age as well as CPB time.