Clinical Trials Logo

Clinical Trial Summary

Pancreaticoduodenectomy (PD) is a complex procedure performed in patients with malignant or benign tumors of the pancreatic head and periampullary region, associated with high morbidity and mortality. Postoperative pancreatic fistula (POPF) is the most common and clinically significant complication following PD. In this study, the investigators aim to predict pancreatic fistula using the C-reactive protein-albumin ratio (CAR). The total number of participants expected to be included in this research comprises patients who underwent PD between 2017 and 2023 and developed pancreatic fistula. The participants invitation is based on the detection of a pancreatic fistula. This study is conducted for research purposes and participation is voluntary. No interventions will be performed on the participants as part of this study; however, we have prepared this form to obtain participant permission to gather certain information. If the participants consent to the use of information for scientific purposes with the guarantee of confidentiality, they will be asked to sign a consent form.


Clinical Trial Description

Pancreaticoduodenectomy (PD) is a complex procedure performed in patients with malignant or benign tumors of the pancreatic head and periampullary region, associated with high morbidity and mortality rates. Despite dramatic advancements in surgical techniques and perioperative management, reported morbidity and mortality rates following PD are 41.56% and 2.88%, respectively, which remain unsatisfactory. Postoperative pancreatic fistula (POPF) is the most common and clinically significant complication following PD. Therefore, accurate and timely prediction of POPF after PD is necessary to reduce secondary mortality from serious complications and optimize individual patient treatment decisions. The C-reactive protein-albumin ratio (CAR) is an inflammatory marker calculated by dividing serum CRP levels by albumin levels and has been associated with poor prognosis in sepsis patients. This study aimed to investigate the predictive significance of CAR for POPF. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06300801
Study type Expanded Access
Source Erol Olcok Corum Training and Research Hospital
Contact
Status No longer available
Phase

See also
  Status Clinical Trial Phase
Not yet recruiting NCT06025071 - Residual Inflammatory Risk-Guided colcHicine in Elderly Trial Phase 4
Not yet recruiting NCT00503282 - Urinary Catheter Exchange on Admission of Septic Elderly With Permanent Catheter Before Initiation of Antibiotics N/A
Recruiting NCT05958368 - Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes N/A
Recruiting NCT06362759 - A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP Phase 2
Completed NCT05329311 - Enhanced Recovery After Thoracic Surgery
Enrolling by invitation NCT04873388 - Early Predictors of Prognostic Course in Patients With COVID-19 in Critical or Semi-intensive Area.
Completed NCT05106738 - Phase Angle and Chronic Intestinal Inflammatory Diseases
Recruiting NCT01232140 - CRP-guided Antibiotic Treatment in COPD Exacerbations Admitted to the Hospital N/A
Completed NCT01028976 - Obesity, Inflammation and Oxidative Stress Phase 3
Completed NCT04213040 - Procalcitonin and Postoperative Outcome After Open-heart Surgery
Completed NCT03985917 - Singing Groups for Seniors: Well-Being, Cognitive Function and Health N/A
Completed NCT05950555 - The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery N/A
Recruiting NCT04939805 - CRP Apheresis in STEMI N/A
Recruiting NCT04133324 - C-protein Reactive for the Detection of Anastomotic Leakage After Surgery for Digestive Cancer