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Plasma Resuscitation Without Lung Injury — PROPOLIS  

Burns Clinical Trial

Official title:
Plasma Resuscitation withOut Lung Injury

Clinical Trial Summary

The treatment of patients with major burns requires resuscitation with massive amounts of fluid, typically a type of salt water that is given by vein. This frequently results in injury to vital organs, especially the lungs and kidneys, and even in death. In this study, the investigators propose to use plasma, a specially prepared blood product made from the liquid part of blood, that has undergone special treatment to reduce the risk of disease transmission. The aims include 1) reduce the amount of fluid given during the first 24 hours after a burn 2) reduce the incidence of lung injury and other complications related to the administration of funds and 3) determine if the blood product has any effect on inflammation. An overall decrease the amount of fluids that burn patients receive should decrease the potential for lung injury, decrease days in the hospital, and improve survival.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04681638
Study type Interventional
Source Coalition for National Trauma Research
Contact Monica Phillips, MBA
Phone 210-884-3410
Email monica@nattrauma.org
Status Recruiting
Phase Phase 4
Start date August 17, 2022
Completion date September 29, 2024
View Details
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