The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

Burns Clinical Trial

Official title:

The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03520816
• Other study ID #: 2016-12
• Status: Completed
• Phase: N/A
• Start date: October 1, 2016
• Est. completion date: April 1, 2017

Study information

• Verified date: May 2018
• Source: Hasan Kalyoncu University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients.

Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study. Participants were divided into two groups: one group was the treatment group and the other was the control group. In the treatment group, patients were admitted to the physiotherapy programme from the first day they have been hospitalised, in addition to their routine treatment (medical, surgery, etc.), for 4 days per week. It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises. The days of treatment were determined as Tuesday, Wednesday, Thursday and Friday. Patients could not be treated on a Monday because that was surgery day. The control group consisted of patients who could not receive physiotherapy due to various reasons. All patients included in the study were evaluated weekly for 6 weeks after admission to the hospital. Parameters such as demographic information, characteristics of burn injury, C-reactive protein, fibronectin, transferrin and prealbumin were evaluated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: April 1, 2017
• Est. primary completion date: February 1, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 21 Years to 47 Years

Eligibility

Inclusion Criteria:

• Age = 18 years

• Major burn injury (according to ABA)

• Conscious patients

Exclusion Criteria:

• Inhalation injury

• Various chronic disorders

• Organ dysfunctions

Related Conditions & MeSH terms

• Burns
• Exercises
• Physiotherapy

Intervention

Other:
• Burn Physiotherapy Protocol
It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Hasan Kalyoncu University

References & Publications (5)

Chinese Burn Association; Chinese Association of Burn Surgeons, Cen Y, Chai J, Chen H, Chen J, Guo G, Han C, Hu D, Huan J, Huang X, Jia C, Li-Tsang CW, Li J, Li Z, Liu Q, Liu Y, Luo G, Lv G, Niu X, Peng D, Peng Y, Qi H, Qi S, Sheng Z, Tang D, Wang Y, Wu J — View Citation

Gillenwater J, Garner W. Acute Fluid Management of Large Burns: Pathophysiology, Monitoring, and Resuscitation. Clin Plast Surg. 2017 Jul;44(3):495-503. doi: 10.1016/j.cps.2017.02.008. Epub 2017 Apr 14. Review. — View Citation

Lee KC, Joory K, Moiemen NS. History of burns: The past, present and the future. Burns Trauma. 2014 Oct 25;2(4):169-80. doi: 10.4103/2321-3868.143620. eCollection 2014. — View Citation

Luzzani A, Polati E, Dorizzi R, Rungatscher A, Pavan R, Merlini A. Comparison of procalcitonin and C-reactive protein as markers of sepsis. Crit Care Med. 2003 Jun;31(6):1737-41. — View Citation

Mandell SP, Gibran NS. Early Enteral Nutrition for Burn Injury. Adv Wound Care (New Rochelle). 2014 Jan 1;3(1):64-70. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fibronectin	Blood test	Changes in fibronectin at 6 weeks later
Primary	Prealbumin	Blood test	Changes in prealbumin at 6 weeks later
Primary	C-reactive protein	Blood test	Changes in C-reactive protein at 6 weeks later
Primary	Transferrin	Blood test	Changes in transferrin at 6 weeks later