Burns Clinical Trial - Assessment of Mechanisms of Improved Wound Healing

Status Completed

Clinical Trial Summary

The purpose of this study is to find ways to improve wound healing and decrease the negative effects of trauma from burn injury.

Clinical Trial Description

This study involves research and the investigators hope to learn the following: how or what effect one or more anabolic ("tissue building") agents have on muscle metabolism, wound healing, and immune function after severe burn. The agents include the following: growth hormone, insulin-like growth factor-1 in combination with its binding proteins, insulin, Beta-adrenergic blockers, Alpha Adrenergic Agonist, anabolic steroids such as testosterone, Oxandrolone and nandrolone, ketoconazole and its derivatives, dehydroepiandrosterone, fenofibrate, diet or the application of skin substitute. ;

Study Design

Related Conditions & MeSH terms

Burns

Clinical Trial Details

NCT number	NCT00673309
Study type	Interventional
Source	The University of Texas Medical Branch, Galveston
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	July 2000
Completion date	April 2013

View Details

See also
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Completed	`NCT05276869` - Reliability and Feasibility of WeeFIM Instrument to Measure Functional Independence in Pediatric Burns
Completed	`NCT04548635` - VR for Burn Dressing Changes at Home	Phase 2/Phase 3
Not yet recruiting	`NCT06076031` - Effects of Applying Streaming Media on Reducing Pain in Patient With Second-degree Burn During Changing Dressing	N/A
Recruiting	`NCT05084248` - Vitamin D Deficiency in Adults Following a Major Burn Injury	Phase 4
Completed	`NCT03113253` - TRANexamic Acid to Reduce Bleeding in BURN Surgery	Phase 4
Recruiting	`NCT04090424` - Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns	N/A
Not yet recruiting	`NCT05649891` - Checklists Resuscitation Emergency Department	N/A
Withdrawn	`NCT03159182` - Study of Silicone Material Inserts To Treat Burn Scars	N/A
Recruiting	`NCT02904941` - Human Amniotic Versus Synthetic Membrane as a Transient Skin Cover for Pediatric Burns	N/A
Completed	`NCT02681757` - Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns	N/A
Recruiting	`NCT01812941` - Evaluation of Mitochondrial Dysfunction in Severe Burn and Trauma Patients	N/A
Completed	`NCT01437852` - StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns	Phase 1
Completed	`NCT01214811` - Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing	Phase 3
Completed	`NCT01061502` - Efficacy Study of a Bioelectric Dressing to Treat Skin Graft Donor Site Wounds	Phase 1/Phase 2
Terminated	`NCT00822796` - Thermogard™ Efficacy Trial	N/A
Terminated	`NCT00824681` - Effect of Music Therapy on Families of Burn Patients	Phase 1
Terminated	`NCT00634166` - Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group	Phase 4
Terminated	`NCT00464386` - Continuous Glucose Monitoring (POC) in the ICU	N/A
Withdrawn	`NCT00216983` - Proline Metabolism in Severely Burned Patients: Effect of Modulated Parenteral Feeding	N/A