Comparison Between Two Treatments for Burning Mouth

Status Completed

Clinical Trial Summary

Introduction: The management of patients with chronic burning mouth is a challenge in clinical dentistry. Objective: To compare the effect of Low Level Laser Therapy (LLLT) and Transcutaneous Electrical Nerve Stimulation (TENS) in the treatment of burning mouth. Materials and Methods: Randomized clinical trial consisting of 25 patients with burning mouth who were treated by TENS (n=12) and by LLLT (n=13). Treatment was carried out weekly for 8 weeks. Two-way ANOVA was used to verify whether there was a significant difference between times T0 (baseline), T1 (after the 4th treatment session), T2 (after the 8th treatment session) and T3 (30 days after the end of treatment) in in relation to symptoms, analyzed using the Visual Analog Scale, unstimulated salivary flow, xerostomia and dysgeusia with TENS and LLLT interventions.

Clinical Trial Description

Experimental group: 20 participants with burning mouth were submitted to transcutaneous electrical nerve stimulation using a device at a frequency of 50 Hertz with intensity modulated according to the patient's comfort ranging from 1 - 4 (pulse amplitude) with a duration of 25 minutes per session, with one session per week, totaling eight weeks of treatment at the end of the study. The device's self-adhesive electrodes were fixed on the participant's face, following the path of the trigeminal nerve branch on the side affected by pain and/or burning. Control group: 20 participants with burning mouth underwent low power laser therapy with punctual applications of infrared laser (L2) (power of 100mW, 808 nm, 6 joules of energy/60 seconds) in the affected region, keeping one centimeter of distance between the points, until the entire area of the complaint was irradiated. being held one session per week, totaling eight weeks of treatment at the end of the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05816200
Study type	Interventional
Source	Universidade Federal do Rio Grande do Norte
Contact
Status	Completed
Phase	N/A
Start date	April 1, 2021
Completion date	June 30, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04475614` - Therapeutic Options for Treatment of Burning Mouth Syndrome	N/A
Completed	`NCT00374673` - Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders	Phase 3
Completed	`NCT02964728` - Botulinum Toxin in Burning Mouth Syndrome	Phase 2
Completed	`NCT04535973` - Hormonal Status and Quality of Life in Female Postmenopausal Patients With Burning Mouth Syndrome
Recruiting	`NCT06040190` - Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome	Phase 4
Not yet recruiting	`NCT05059418` - Burning Mouth Syndrome - New Diagnostic Criteria and Treatment	N/A
Recruiting	`NCT01867151` - Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome	N/A
Completed	`NCT05872789` - Impact of Diazepam 1% Oral Gel Efficacy in Burning Mouth Syndrome	N/A
Completed	`NCT05871580` - Effect to the Photobiomodulation in the Burning Mouth Syndrome	N/A
Recruiting	`NCT05309070` - The Efficacy of N-acetyl-cysteine in the Treatment of Burning Mouth Syndrome	N/A
Completed	`NCT05399238` - Thermography and Burning Mouth Syndrome
Completed	`NCT02382029` - Acupuncture Versus Clonazepam in Burning Mouth Syndrome	Phase 0
Completed	`NCT02580734` - Efficacy of Melatonin in Burning Mouth Syndrome (BMS)	N/A
Recruiting	`NCT05819697` - Reducing Patient Memory Recall in the Burning Mouth Patient Population
Completed	`NCT02757612` - Study Evaluating the Laser Diode Effect Burning Mouth Syndrome	N/A
Completed	`NCT00862576` - A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome	N/A
Not yet recruiting	`NCT04189367` - Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine and Western Medicine	Phase 3
Completed	`NCT00001524` - Thalidomide to Treat Oral Lesions in HIV-Infected Patients	Phase 2
Recruiting	`NCT04481841` - Head Yuanshi Dian Therapy in Burning Mouth Syndrome	Early Phase 1
Completed	`NCT02686359` - Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)	N/A