Burn Clinical Trial
Official title:
Colloid Improves Organ Function by Reducing the Elevation of Intra-abdominal Pressure in Resuscitation of Critical Burn Patients
The present study was to evaluate the effectiveness of colloid compared with crystalloids for fluid resuscitation in critical burn patients with total burn surface area ≥50%.
Extensive burn patients are some of the most challenging critically ill patients who may have multiple-system organ failure with life-threatening complications.Over time, several resuscitation formulae have been proposed to guide burn resuscitation and the best known ones are Parkland and Evans formulae. The main controversy between the two formulae also focuses on whether to infuse the colloid in the first 24 h.Controversy continues and the conflicting results left many clinicians unsure about the effect of colloids on fluid resuscitation in extensive burn patients who suffer higher risk of hypovolaemia, abdominal compartment syndrome (ACS), multiple organs dysfunction and mortality. To address this uncertainty, we conducted a prospective, randomized, controlled clinical trial to compare fluid resuscitation in extensive burns guided by Parkland formulae with TMMU formulae as a modified Evans formula routinely used in China. ;
Observational Model: Case Control, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT01302457 -
Oral Care Study on Burn Patients
|
N/A | |
Completed |
NCT02729259 -
H2O VR for Burns 2015
|
N/A | |
Completed |
NCT01965340 -
Impact of Therapeutic Drug Monitoring on Anti-Infective Agents Amongst Severely Burned Patients Requiring ICU Admission
|
N/A | |
Withdrawn |
NCT01225107 -
Effect of Cranberry Extract on Infections in Burn Patients
|
N/A | |
Completed |
NCT01983280 -
The Effect of Healing Touch on Sleep Patterns of Pediatric Burn Patients
|
N/A | |
Completed |
NCT00591448 -
Study in the Use of Virtual Reality as an Adjunct to Pain Control in Burn Patients
|
N/A | |
Active, not recruiting |
NCT02083900 -
Use of Banana Leaf Dressing on Donor Site Wounds
|
Phase 2 | |
Completed |
NCT00242970 -
Hypertrophic Scarring After Facial Burn
|
Phase 2 | |
Completed |
NCT00585325 -
Instilled Lidocaine vs Placebo for Pain Management During Vacuum Assisted Closure (VAC) Dressing Changes
|
N/A | |
Terminated |
NCT00591162 -
Bone Disease in Severely Burned Children
|
Phase 2/Phase 3 | |
Terminated |
NCT02452255 -
Fenofibrate and Propranolol in Burn Patients
|
Phase 2/Phase 3 | |
Completed |
NCT03183622 -
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-BI-101 Clinical Trial
|
N/A | |
Completed |
NCT02427659 -
VR High Tech Pain Control Burn Wound Care
|
N/A | |
Not yet recruiting |
NCT00253279 -
Alterations in Protein Synthesis Rates of Burn Patients Measured Over Time Using PET Scans
|
Phase 1 | |
Completed |
NCT04516148 -
A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting
|
Phase 4 | |
Withdrawn |
NCT02029261 -
Observational Study of Insulin Resistance and Muscle Wasting After Burn Injury
|
||
Completed |
NCT00993889 -
Virtual Reality Analgesia During Pediatric Physical Therapy
|
N/A | |
Terminated |
NCT01062191 -
Altrazeal Range of Motion Study Comparing With Typical Carboxymethyl
|
N/A | |
Completed |
NCT02394873 -
A Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Deep Second-degree Burn Wound
|
Phase 1 | |
Completed |
NCT00239668 -
Multicenter Benchmarking of Functional and Psychosocial Outcomes of Pediatric Burn Survivors
|