Bullous Keratopathy Clinical Trial
Official title:
Amniotic Membrane Transplant in Symptomatic Bullous Keratopathy Patients: Confocal Microscopy & AS-OCT Long Term Results
Verified date | March 2018 |
Source | Prince of Wales Hospital, Shatin, Hong Kong |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
A retrospective study including 22 patients who have undergone amniotic membrane transplant in our unit up till 2016. Confocal microscopy and anterior segment optical coherence tomography (ASOCT) were performed to assess the retention of amniotic membrane and to detect any corneal structural changes. Comparison was made with 5 controls who had bullous keratopathy awaiting endothelial keratoplasty.
Status | Completed |
Enrollment | 27 |
Est. completion date | November 30, 2016 |
Est. primary completion date | November 30, 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - All patients who have undergone amniotic membrane transplant in our cluster up till 2016. - Patients who have bullous keratopathy on conservative treatment such as lubricants, bandage contact lens Exclusion Criteria: - patients who refuse to participate in the study, have passed away or cannot return for the clinical assessment will be excluded. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Prince of Wales Hospital, Shatin, Hong Kong |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Amniotic membrane retention | Amniotic membrane retention in the cornea was assessed with confocal microscopy | from date of operation till 2016 | |
Secondary | Pain | pain score (from 0-10, scale interval 1, 0 no pain, 10 most painful)reduction after amniotic membrane tranplant | from date of operation till 2016 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03248037 -
Trial of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation
|
Phase 3 | |
Enrolling by invitation |
NCT05956535 -
Air Optix® Night and Day® Aqua Therapeutic Wear
|
||
Recruiting |
NCT02020044 -
Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)
|
N/A | |
Recruiting |
NCT03407755 -
Air Versus SF6 for Descemet's Membrane Endothelial Keratoplasty (DMEK)
|
N/A | |
Completed |
NCT01448213 -
Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK)
|
Phase 2 | |
Completed |
NCT01926535 -
Amniotic Membrane Graft In Syntomathic Bullous Keratopathy
|
Phase 2 | |
Completed |
NCT01106274 -
The Effects of Riboflavin/ Ultraviolet-A Corneal Cross-linking on the Signs and Symptoms of Bullous Keratopathy
|
N/A | |
Completed |
NCT03763721 -
The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation
|
N/A | |
Completed |
NCT05891106 -
AONDA Therapeutic Indication Study I
|
||
Active, not recruiting |
NCT04894110 -
Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema
|
Phase 1 | |
Completed |
NCT00659308 -
Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous Keratopathy
|
N/A | |
Completed |
NCT01122043 -
The SNEC DSAEK EndoGlide Clinical Trial
|
N/A | |
Completed |
NCT00800111 -
Study of Endothelial Keratoplasty Outcomes
|
N/A | |
Recruiting |
NCT05636579 -
Study to Assess Safety and Tolerability of Multiple Doses of EO2002
|
Phase 1 | |
Recruiting |
NCT04319848 -
Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty
|
Phase 1 | |
Recruiting |
NCT05436665 -
The Belgian Endothelial Surgical Transplant of the Cornea
|
N/A | |
Not yet recruiting |
NCT02736877 -
Corneal Transplantation Guided by OCT RESCAN
|
N/A |