Effects of Different Ventilatory Strategy During Bronchoscopy

Bronchoscopy Clinical Trial

Official title:

Effects of Different Ventilatory Strategy During Bronchoscopy

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05956301
• Other study ID #: 20230618
• Status: Not yet recruiting
• Phase: N/A
• Start date: July 20, 2023
• Est. completion date: June 30, 2025

Study information

• Verified date: July 2023
• Source: The First Affiliated Hospital of Guangzhou Medical University
• Contact: Liya Lu
• Phone: +86-020-83062885
• Email: 2412183636[@]qq.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic procedures.

Our study aim was to evaluate the efficacy and complications of High-flow nasal oxygen (HFNO) via Supraglottic jet oxygenation and ventilation (SJOV)during flexible bronchoscopy.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 150
• Est. completion date: June 30, 2025
• Est. primary completion date: June 30, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• need for bronchial endoscopy

Exclusion Criteria:

• life-threatening cardiac aritmia or acute miocardical infarction within 6 weeks need for invasive or non invasive ventilation presence of pneumothorax or pulmonary enphisema or bullae recent (within 1 week) thoracic surgery presence of chest burns presence of tracheostomy pregnancy nasal or nasopharyngeal diseases dementia lack of consent or its withdrawal

Related Conditions & MeSH terms

• Bronchoscopy

Intervention

Device:
• Conventional Oxygen Therapy
Conventional Oxygen Therapy will be administered through Nasal catheter
• High-flow nasal oxygen
High Flow Nasal Cannula will be administered
• Supraglottic jet oxygenation and ventilation
Nasal jet tube will be administered

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The First Affiliated Hospital of Guangzhou Medical University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Compare the intraoperative oxygenation.	The study will monitor the SpO2, heart rate(HR) and mean arterial pressure (MAP) during the procedure.	During bronchoscopy, an average of 0.5 hour.
Secondary	Arterial blood gases	Arterial blood gas analysis will be monitored at end of of procedure.	At end of of bronchoscopy,an average of 0.5 hour after bronchoscope insertion.
Secondary	Assess the regional ventilation distribution by Electrical impedance tomography .	Measurements will be done after bronchoscope insertion and at the end of the procedure.	During bronchoscopy, an average of 0.5 hour.