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Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome — Surfactant 1  

Bronchopulmonary Dysplasia Clinical Trial

Official title:
Efficacy and Safety of Exosurf Neonatal and Survanta for the Treatment of Respiratory Distress Syndrome

Clinical Trial Summary

The purpose of this study is to compare the efficacy of two surfactants, Exosurf Neonatal (Burroughs Wellcome Co.) and Survanta (Ross Laboratories), for the treatment of neonatal respiratory distress syndrome.

Clinical Trial Description

The NICHD Neonatal Research Network conducted a randomized trial at 11 centers comparing the efficacy of two surfactants -- Exosurf Neonatal (Burroughs Wellcome Co.) and Survanta (Ross Laboratories) -- for the treatment of neonatal respiratory distress syndrome. Newborn infants with birth weights of 501-1500g with respiratory distress syndrome who were receiving assisted ventilation with 30% oxygen or more within 6 hours of birth were enrolled between January 1991 and January 1992. Infants were randomly assigned to receive up to four intratracheal doses of either Exosurf Neonatal or Survanta. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01203358
Study type Interventional
Source NICHD Neonatal Research Network
Contact
Status Completed
Phase Phase 2/Phase 3
Start date January 1991
Completion date January 1992
View Details
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