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Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia — CURDYS  

Bronchopulmonary Dysplasia Clinical Trial

Official title:
Exogenous Surfactant in Very Preterm Neonates Presenting With Severe Respiratory Distress in Prevention of Bronchopulmonary Dysplasia

Clinical Trial Summary

Advances in perinatal care have made it possible to improve the survival of the most immature neonates, but at the cost of an increase in the population at risk of developing bronchopulmonary dysplasia (BPD). Measures that have attempted to limit the development of BPD are not always effective, or related to major side effects. The physiopathological factors that are identified in BPD should, in theory, respond to surfactant. Therefore, the use of an exogenous surfactant in neonates presenting with pulmonary disease requiring mechanical ventilation, leading to a significant risk of BPD, should allow earlier extubation and thus promote pulmonary healing and growth.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01039285
Study type Interventional
Source Maternite Regionale Universitaire
Contact
Status Completed
Phase Phase 4
Start date December 2009
Completion date June 2022
View Details
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