Chest Physiotherapy in Bronchiolitis

Status Completed

Clinical Trial Summary

Randomized trial of chest physiotherapy in outpatients with bronchiolitis under two years of age, during two consecutive seasonal outbreaks.

Clinical Trial Description

A randomized controlled trial was conducted (following CONSORT Statement) in the Paediatric Emergency Department of Centro Hospitalar Universitário São João-Porto (CHUSJ), a tertiary care hospital, during the period from December to March in 2011 and 2012. Ethical approval was obtained from the Ethics Committee of Centro Hospitalar Universitário São João-Porto. Children up to 2 years of age, both genders, with a diagnosis of acute bronchiolitis based on clinical findings, including wheezing or wheezing with crackles, respiratory distress and alteration of feeding condition, were signalized by the physician who met them at the emergency room. Then, the main investigator of the study interviewed the caregivers and informed about the aims and procedures of the study, after a formal written consent in accordance with the Declaration of Helsinki was sign by all the caregivers. Severity grade was established with the Kristjansson Respiratory Score which variate from light to severe, being the light to moderate selected to study. Randomization in intervention or control group was made by the method of permuted-blocks. All children were assessed in a calm environment, while awake and not crying, and were submitted to a standard assessment protocol consisting of a clinical demographic data collection by interview of parents and the application of the Kristjansson Respiratory Score. All children underwent the same medical treatment protocol at the pediatric emergency department (PED), consisting in nebulization with medication, during the emergency room episode, and counselled in the subsequent one or two weeks and were followed during two weeks after discharge from PED, being reassessed at the end of the two weeks. Children from Intervention Group (IG) underwent a standard intervention chest physiotherapy protocol performed by a physiotherapist, consisting on the techniques: prolonged slow expiration (PSE), rhinopharyngeal retrograde clearance (RRC) and provoked cough (PC). ;

Study Design

Related Conditions & MeSH terms

Bronchiolitis

Clinical Trial Details

NCT number	NCT04260919
Study type	Interventional
Source	Universidade do Porto
Contact
Status	Completed
Phase	N/A
Start date	December 2010
Completion date	March 2012

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04989114` - Nasal Bubble Continuous Positive Airway Pressure in Reducing Respiratory Distress in Children With Bronchiolitis	N/A
Recruiting	`NCT06016244` - Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial	N/A
Not yet recruiting	`NCT05902702` - Isotonic Saline for Children With Bronchiolitis	N/A
Recruiting	`NCT02366715` - Treatment Of Bronchiolitis With Heated Humidified High Flow Nasal Cannula - Prospective And Retrospective Research	Phase 3
Terminated	`NCT02219334` - Comparing Nasal Suction Devices in Children With Bronchiolitis: A Pilot Study	N/A
Recruiting	`NCT01944995` - Work of Breathing in Nasal CPAP Versus High Flow Nasal Prong in Infants With Severe Acute Bronchiolitis	N/A
Terminated	`NCT02834819` - Nebulized 3% Hypertonic Saline vs. Standard of Care in Patients With Bronchiolitis	N/A
Terminated	`NCT01757496` - Cough Assist in Bronchiolitis	N/A
Not yet recruiting	`NCT01414322` - Documentation of Continuous Wheeze and Cough Dynamics in Pediatric ER SOB Patients	N/A
Completed	`NCT00369759` - An Epidemiological Study to Evaluate the RSV-Associated Lower Respiratory Track in Infections in Infants	N/A
Completed	`NCT00347880` - Atrial and Brain Natriuretic Peptides in Bronchiolitis	Phase 1
Recruiting	`NCT05548036` - A Feasibility RCT of Aerobika Verses ACBT in People With COPD	N/A
Active, not recruiting	`NCT04302207` - The ROUTT-B (Reduce Over-Utilized Tests and Treatments in Bronchiolitis) Study	N/A
Completed	`NCT02858531` - Predictive Tracking of Patient Flow in the Emergency Services During the Virus Winter Epidemics
Withdrawn	`NCT05994183` - The Bronchiolitis in Hospitalized Infants Study	Early Phase 1
Terminated	`NCT03614507` - Automation Oxygen Flow Titration in Spontaneously Breathing Infants	N/A
Completed	`NCT02856165` - High-flow Nasal Oxygen Therapy in Hospitalized Infant With Moderate-to-severe Bronchiolitis	N/A
Recruiting	`NCT05909566` - Respiratory Support and Treatment for Efficient and Cost-Effective Care	N/A
Recruiting	`NCT04437641` - Impact of Pediatrician Intervention on the Smoking Habits of Parents of Sick Children
Not yet recruiting	`NCT06083077` - Chest and Abdominal Wall Strapping in Infant With Bronchiolitis	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.