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NCT01684527 Clinical Trial

Immature Myeloid Cells in Respiratory Syncytial Virus Bronchioliltis

Bronchiolitis Clinical Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT01684527
Other study ID # 0039-12-HYMC
Secondary ID
Status Not yet recruiting
Phase N/A
First received September 5, 2012
Last updated September 10, 2012
Start date October 2012
Est. completion date January 2014

Study information
Verified date September 2012
Source Hillel Yaffe Medical Center
Contact n/a
Is FDA regulated No
Health authority Israel: Ministry of Health
Study type Observational

Clinical Trial Summary

The investigators hypothesize that Respiratory Syncytial Virus (RSV) infection may influence the population of lung immature myeloid cells and dendritic cells in a way that will impair their ability to invoke an effective immune response and lead to prolonged inflammation, angiogenesis and scarring. This may lead in turn to disturbed lung function.

Our aim is to determine the presence and phenotype of immature myeloid cells present in respiratory secretions of children with RSV bronchiolitis as compared to non-RSV bronchiolitis and healthy controls.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 55
Est. completion date January 2014
Est. primary completion date January 2014
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group N/A to 2 Years
Eligibility Inclusion Criteria:

- Bronchiolitis

Exclusion Criteria:

- Chronic disease

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Other:
• Respiratory secretions obtained

Locations
Country Name City State
Israel Hillel Yaffe Medical Center Hadera

Sponsors (1)
Lead Sponsor Collaborator
Hillel Yaffe Medical Center

Country where clinical trial is conducted

Israel, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of Immature Myeloid Cells in Respiratory Secretions Respiratory secretions obtained from child presenting with bronchiolitis will be examined for the presence of immature myeloid cells Participants will be followed for the duration of hospital stay, an expected average of one week No
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