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Exhaled Breath Condensate Assessment in Stable Non-Cystic Fibrotic Bronchiectasis

Bronchiectasis Clinical Trial

Official title:
Exploring the Relationship Between pH of Exhaled Breath Condensate and Disease Severity as Well as Prognosis of Bronchiectasis

Clinical Trial Summary

The measurement of markers in the expired breath condensate has proven to be a useful method for assessing and monitoring airway inflammation. The aim of this study is to determine the amounts of pH in the expired breath condensate of patients with bronchiectasis, and the relationship between pH and the severity of bronchiectasis.

Clinical Trial Description

The aim of this study is to determine the amounts of pH in the expired breath condensate of patients with bronchiectasis, and the relationship between pH and the severity of bronchiectasis. Further clarify the link between EBC pH and the risk of future acute exacerbations, mortality and lung function decline through a one-year follow-up. Hoping to explore new validated biomarkers of the disease severity and progression in bronchiectasis. During the observation, EBC pH and other valid indicators will be measured when patients were enrolled. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03643263
Study type Observational
Source Shanghai Pulmonary Hospital, Shanghai, China
Contact
Status Completed
Phase
Start date June 25, 2018
Completion date July 2, 2020
View Details
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