Evaluation of Medical and Nursing Management for Bronchiectasis

Bronchiectasis Clinical Trial

Official title:

Evaluation of Medical and Nursing Management for Bronchiectasis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03550417
• Other study ID #: QElizabethH
• Status: Completed
• Start date: June 22, 2015
• Est. completion date: March 28, 2023

Study information

• Verified date: March 2023
• Source: The Queen Elizabeth Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this research is to retrospectively evaluate current clinical care of Bronchiectasis (non-cystic fibrosis [CF]) in adults from a multidisciplinary management perspective. This evaluation aims to address the important gaps in current clinical care in 2011, 2013 and July 2016- Jun2017. The primary outcome of this evaluation is to compare the efficacy of current multidisciplinary clinical practice to the British Thoracic Society (BTS) & Thoracic Society of Australia and New Zealand (TSANZ) guidelines for bronchiectasis. Secondary outcomes of this evaluation will determine the impact of clinical care in 2011, 2013 and July2016-June2017 through quantification of:hospital utilization for using hospital admission data, average length of stay, readmission rates within 28 days, emergency service attendance, outpatient review, exacerbations use of antibiotics, use of Hospital and Home (H@H), number of contacts with the respiratory nursing service and type of contacts with the respiratory nursing service.

Description:

Project design: The study will be a 12 month retrospective observational cohort study conducted through a review of medical records, internal respiratory databases and electronic hospital patient record (OACIS, HOMER & EPAS). Participants: Participants in the study will include all patients who have emergency service presentations or admissions to The Queen Elizabeth Hospital (TQEH) with new or existing bronchiectasis in 2011(Jan 1st to Dec 31st). This will be repeated using the same criteria in 2013. An additional year of July2016- Jun2017 has been added for recency of management and to assess if change occurred with introduction of electronic patient record. Data collection: Demographics, clinical data, hospital service utilization, and clinical outcomes such as exacerbation frequency and disease progression. All data will be extracted into a standardized data extraction form, which a random subset will be checked by a second researcher.Analysis of results:Demographic and descriptive data will be given in means + standard deviation and compared using a two-tailed and Student t-test. Categorical variables will be compared using chi-squared or Fisher exact tests, and when appropriate the Mann Whitney U test for non-parametric data. Statistical significance will be determined using an alpha of p <0.05. All analyses will be examined using SPSS software (version x). A subgroup analysis for primary and secondary admission diagnosis will also be performed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 65
• Est. completion date: March 28, 2023
• Est. primary completion date: March 28, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria: Admission or attendance to emergency services at The Queen Elizabeth hospital with primary or secondary diagnosis of Bronchiectasis in 2011. Repeated using same criteria in 2013 and July2016-June2017

Exclusion Criteria: Patients who do not have bronchiectasis. Patients with traction bronchiectasis. Patients who do not have outpatient follow up. Patients who have follow up by private physicians or other hospitals and records are unavailable.

Related Conditions & MeSH terms

• Bronchiectasis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The Queen Elizabeth Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage of patients with bronchiectasis guideline compliant care	Percentage of patients who meet guideline compliant care for management of bronchiectasis based in TSANZ and BTS guideline recommendations for outpatient management	12 months
Secondary	Number of admissions	Service outcome includes number of emergency department attendance and admissions	12 months
Secondary	Impact of bronchiectasis outpatient management on patient outcomes	Frequency of exacerbation reported in patient case notes (electronic and hard copy) extracted by two respiratory nurses	12 months
Secondary	Number of outpatient (OPD) attendances	Service outcome includes respiratory and all cause OPD attendances	12 months
Secondary	Patient mortality	Mortality of patients from qualifying admission to present day	0 years up to 4 to 7 years dependent on qualifying year