Evaluation Of The Lung Microbiome In NTM Bronchiectasis

Status Recruiting

Clinical Trial Summary

A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease. In a cohort of 200 subjects suspected of having pulmonary NTM disease, the investigators will evaluate the airway microbiome using an aliquot of the induced sputum and upper airway samples. Since induced sputum may reflect different regions of the upper/lower airways, the investigators will evaluate the upper and lower airway microbiome in a subgroup (case-control group) of patients using samples obtained through upper airway sampling and bronchoscopy, respectively.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02779478
Study type	Observational
Source	NYU Langone Health
Contact	Lisa Guiterrez
Email	Lira.Gutierrez@nyulangone.org
Status	Recruiting
Phase
Start date	October 1, 2014
Completion date	July 2026

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05034900` - Does Addition of Oscillatory Positive Expiratory Pressure (OPEP) Device to a Chest Physiotherapy Program Provide Further Health Benefits in Children With Bronchiectasis?	N/A
Recruiting	`NCT04101448` - Prevalence of Bronchiectasis in COPD Patients
Withdrawn	`NCT03376204` - Pain Mechanisms in Patients With Bronchiectasis
Completed	`NCT02550821` - Comparison of Physical Activity Level Between Patients With Bronchiectasis and Healthy Subjects
Completed	`NCT02656992` - Effects of High Intensity Inspiratory Muscle Training on Exercise Capacity in Patients With Bronchiectasis	N/A
Completed	`NCT01615484` - Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability	N/A
Completed	`NCT02282202` - Evaluation of Oscillatory Positive Expiratory Pressure (oPEP) in Bronchiectasis and COPD	N/A
Completed	`NCT02048397` - Pulmonary Rehabilitation Program (PRP) Versus PRP Plus Nutritional Supplementation in Patients With Bronchiectasis	N/A
Recruiting	`NCT01761214` - Bacteriology and Inflammation in Bronchiectasis	N/A
Recruiting	`NCT02527486` - Seoul National University Airway Registry	N/A
Completed	`NCT01578681` - ELTGOL and Bronchiectasis. Respiratory Therapy	N/A
Completed	`NCT01854788` - 3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis	N/A
Completed	`NCT00769119` - A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis	Phase 2
Terminated	`NCT00524095` - Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of Prophylaxis	Phase 2
Completed	`NCT01117493` - Expert Patient Self-management Programme Versus Usual Care in Bronchiectasis	N/A
Recruiting	`NCT00129350` - Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation	Phase 1
Completed	`NCT00656721` - Respiratory Mechanics Effects of Flutter Valve in Bronchiectasis Patients	N/A
Completed	`NCT04081740` - Biological Determinants of Sputum Rheology in Chronic Airway Diseases
Enrolling by invitation	`NCT02546297` - Comparisons of Inhaled LAMA or LAMA+LABA or ICS+LABA for COPD With Bronchiectasis	Phase 4
Completed	`NCT03628456` - Effect of HFCWO Vests on Spirometry Measurements	N/A