Bronchiectasis Clinical Trial
Official title:
Inspiratory Flow Rates and Volumes in Subjects With Bronchiectasis Using Low and High Resistance Dry Powder Inhaler Devices
Adequate administration of drugs via dry powder inhalers is dependent on adequate
inspiratory flow rates and volumes. These vary according to the device being used and its
resistance. The dry powder inhaler device under investigation is a device approved by the
Therapeutic Goods Administration (ARTG no. 196255) for use with dry powder mannitol. Dry
powder mannitol is currently being investigated as a treatment for bronchiectasis. We wish
to measure the inspiratory flow characteristics of both the low and high resistance devices
amongst a group of subjects with bronchiectasis.
We propose that the majority of subjects investigated with varying lung function will
achieve adequate flow during a controlled inspiration.
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