NCT03638063 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Fowles HE, Rowland T, Wright C, Morice A
Tussive challenge with ATP and AMP: does it reveal cough hypersensitivity? Eur Respir J. 2017 Feb 8;49(2). pii: 1601452. doi: 10.1183/13993003.01452-2016. Print 2017 Feb.
Fuller RW
Cough provocation tests: their clinical value. Pulm Pharmacol Ther. 2002;15(3):273-6. Review.
Guan WJ, Gao YH, Xu G, Lin ZY, Tang Y, Li HM, Lin ZM, Zheng JP, Chen RC, Zhong NS
Capsaicin cough sensitivity and the association with clinical parameters in bronchiectasis. PLoS One. 2014 Nov 19;9(11):e113057. doi: 10.1371/journal.pone.0113057. eCollection 2014.
Torrego A, Haque RA, Nguyen LT, Hew M, Carr DH, Wilson R, Chung KF
Capsaicin cough sensitivity in bronchiectasis. Thorax. 2006 Aug;61(8):706-9. Epub 2006 Apr 6.

Adenosine Triphosphate and Capsaicin Cough Provocation Test for Identifing Patients With Chronic Cough Who Have Differential Responses to Purinergic Receptor Antagonists: a Randomized, Cross-over, Single-blind Trial

Details for clinical trial NCT03638063

Clinical trial NCT03638063 - References