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Bronchial Asthma clinical trials

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NCT ID: NCT06326632 Completed - Bronchial Asthma Clinical Trials

Comparative Effectiveness Study of Constant-Load Versus Graded Aerobic Exercise in Obese Children With Bronchial Asthma

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

This study aimed to compare the effect of constant-load aerobic exercise (CL-AE) and graded aerobic exercise (G-AE) on cardiopulmonary fitness, and functional capacity in a cohort of obese children with bronchial asthma (BA). A total of 78 children with BA were randomly assigned to the CL-AE group (n = 26, who underwent moderate-intensity aerobic training with the training load maintained at the same level throughout the entire program, besides the respiratory re-training program), the G-AE group (n = 26, received an intensity- and duration-graded aerobic training in addition to the respiratory re-training program), or the control group (n = 29, who only engaged in a respiratory re-training program). Interventions were administered three times/week for 12 successive weeks. The cardiopulmonary fitness and functional capacity were evaluated in the three groups before and after the completion of the assigned interventions.

NCT ID: NCT06005506 Completed - Adhd Clinical Trials

National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.

sPATIALS3
Start date: October 1, 2021
Phase: N/A
Study type: Interventional

The objective of the study will be to understand whether a supplementation of the diet with an active symbiotic, i.e. characterized by a mix of probiotics and a specially selected fiber with prebiotic activity combined with a vegetable extract with beneficial activities on carbohydrate and lipid metabolism, can reduce the relative inflammatory potential and improve absorption, intestinal motility and bowel habit of patients with various pathological conditions, such as ALS, ADHD and bronchial asthma.

NCT ID: NCT05428956 Completed - Bronchial Asthma Clinical Trials

Two Inhalation Methods Using a Pressurized Metered Dose Inhaler With Valved Holding Chamber to Assess Improvement in Lung Function After SABA Administration in Bronchial Asthma

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

Bronchial asthma is a chronic inflammatory disorder characterized by recurrent reversible episodes of breathlessness, wheezing, chest tightness and/ or cough. The prevalence of asthma in India is about 2%, and asthma is responsible for significant morbidity. A diagnosis of asthma is made in the presence of clinical symptoms with or without reversibility on spirometry assessment.1 Treatment comprises of inhaled medications that are used either as controller medication or a reliever medications. In a recent study involving asthmatic children, single maximal inhalation with breath hold was not found to be superior to tidal breathing for improvement in peak expiratory flow rates. The authors hypothesized that both the techniques would improve FEV1 similarly.

NCT ID: NCT05373511 Completed - Bronchial Asthma Clinical Trials

Assessing Body Posture and Postural Balance Among Young Adults With Bronchial Asthma

Start date: February 1, 2022
Phase:
Study type: Observational

The purpose of the study is to assess the relationship between body posture and dynamic balance in adults with childhood-onset asthma and compare them to a non-asthmatic control group matched for gender, age, weight, and height.

NCT ID: NCT05366491 Completed - Bronchial Asthma Clinical Trials

IL-38 Evaluation as a Biomarker in Pediatric Asthma

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the associations between serum IL-38 levels and different variables of asthma in children such as laboratory variables, pulmonary function test results, the diagnosis of asthma, and in correlation with disease severity.

NCT ID: NCT05270278 Completed - Bronchial Asthma Clinical Trials

Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy

Start date: August 16, 2022
Phase:
Study type: Observational

The goal of this study is to identify reliable, valid, easily measurable, interpretable, and useful biomarkers in peripheral blood and exhaled air by people with severe asthma for a more accurate description of the pathogenetic processes of asthma-related to the inflammatory endotype and the choice of biologic therapy.

NCT ID: NCT05212558 Completed - Bronchial Asthma Clinical Trials

Coupled Inspiratory and Expiratory Muscle Training in Children With Bronchial Asthma

Start date: August 2, 2020
Phase: N/A
Study type: Interventional

This study was designed to assess the effect of inspiratory and expiratory muscle training in the same cycle on respiratory muscle strength, pulmonary functions, perception of asthma symptoms in children with bronchial asthma. Fifty-one children with bronchial asthma were randomly allocated to the unloaded respiratory muscle training (Placebo training group; n = 17), inspiratory muscle training alone (inspiratory muscle training group; n = 17), or combined inspiratory and expiratory muscle training in the same cycle (combined training group; n = 17). All groups were assessed for respiratory muscle strength, pulmonary functions, and asthma symptoms.

NCT ID: NCT05180877 Completed - Bronchial Asthma Clinical Trials

Asthma During Pregnancy; Impact of Severity

Start date: April 1, 2019
Phase:
Study type: Observational

bronchial asthma (BA) may affect pregnancy and this affection may increase with increasing asthma severity. This study was designed to detect the effect of asthma severity on the course of asthma during pregnancy and its effect on the pregnancy and perinatal outcome

NCT ID: NCT05088512 Completed - Bronchial Asthma Clinical Trials

The Role of Genetic Factors in the Development of Bronchial Asthma in the Kazakh Population

Start date: October 23, 2021
Phase:
Study type: Observational

To research for a genetic marker of bronchial asthma, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with bronchial asthma and normal control will be performed.

NCT ID: NCT04958616 Completed - Bronchial Asthma Clinical Trials

House Dust Mites Sensitization and Level of Asthma Control and Severity in Children

Start date: February 1, 2018
Phase:
Study type: Observational

In this study we aimed to assess the clinical and laboratory profile of some Egyptian asthmatic children who are sensitized to house dust mites and determine the association of HDM sensitization and severity of asthma according to recent GINA guidelines.