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Proof of Concept Study of Re-treatment in BRVO With Ranibizumab Guided by OCT — RabOCT  

Branch Retinal Vein Occlusion Clinical Trial

Official title:
A Randomized, Controlled Interventional Phase 2b (Proof of Concept) Study of the Efficacy, Safety, and Tolerability of Repeated Intravitreal Administration of Ranibizumab Guided by Morphological Changes Documented by Optical Coherence Tomography (OCT) in Subjects With Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)

Clinical Trial Summary

The aim of the trial is to evaluate the efficacy and safety of intravitreal injections of ranibizumab for the treatment of macular edema due to BRVO if the re-treatment regimen is guided by morphological macular changes detected by OCT compared to re-treatment according to SmPC defined re-treatment criteria (in case of increase of CRT and concomitant decrease of BCVA).

Clinical Trial Description

In a prospective, randomized, interventional, controlled phase IIb clinical the functional results of treatment with ranibizumab in patients with macular edema due to branch retinal vein occlusion when given according to morphological changes detected by OCT compared to standard re-treatment criteria according to SmPC ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01968239
Study type Interventional
Source University of Leipzig
Contact
Status Completed
Phase Phase 2
Start date October 2013
Completion date December 20, 2016
View Details
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