Brain Tumor Clinical Trial
Official title:
18F-DOPA-PET in Non-tumoral and Tumoral Brain Lesions
Background: 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography
(PET) can identify well low and high grade brain tumors. However, increased FDOPA uptake has
been reported in non-tumoral brain lesions. The aim was to analyse FDOPA-PET in patients with
non-tumoral brain lesions and to compare them with patients with (low and high grade) brain
tumors.
Methods: retrospective analyse. Patients consecutively recruited with suspected primary brain
tumor (based on clinical and MRI findings) referred for FDOPA-PET at Nimes university
Hospital between June 2015 and June 2019. FDOPA-PET parameters (maximum and mean lesion
standardized uptake values [SUV] and ratios comparing lesion with different background uptake
SUV) and thresholds were analysed in search for those offering optimal discrimination between
non-tumoral and tumoral lesions.
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