Evaluation of Intra Axial Brain Masses Based on Magnetic Resonance in Adults

Brain Tumor Clinical Trial

Official title:

Impact of Advanced Neuroimaging Techniques in Evaluation of Intra Axial Brain Masses Based on Magnetic Resonance Diagnostic Strategy in Adults

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03166592
• Other study ID #: IAM
• Status: Recruiting
• Phase: N/A
• First received: May 24, 2017
• Last updated: August 13, 2017
• Start date: July 1, 2017
• Est. completion date: September 2019

Study information

• Verified date: August 2017
• Source: Assiut University
• Contact: Ahmed Abbas, MD
• Phone: 00201003385183
• Email: bmr90[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Although the Magnetic resonance imaging with contrast is the gold standard for diagnosis of intra axial brain masses. The conventional Magnetic resonance imaging appearances of intra axial brain masses can be non-specific and even the use of contrast agent is of limited benefit.

Contrast enhancement reflects only disruption of blood brain barrier. One third of high-grade malignancies are non-enhanced and may non-neoplastic lesions show contrast enhancement.

Reliable differentiation of neoplastic from non-neoplastic brain masses, or of high grade from low grade tumor, is difficult with conventional Magnetic resonance imaging

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: September 2019
• Est. primary completion date: July 2019
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

1. Inclusion criteria:

• An intra axial space occupying lesion/lesions detected on conventional structural imaging

2. Exclusion criteria:

• MRI contraindications (as pace maker or claustrophobia).

• Contrast hypersensitivity

• Impaired renal function.

• Pediatric age group

Related Conditions & MeSH terms

• Brain Tumor

Intervention

Device:
• Magnetic resonance imaging with contrast
injection of gadolinium contrast then acquisition of images with magnetic resonance imaging then spectroscopy

Locations

Country	Name	City	State
Egypt	Ahmed Abbas	Assiut	Cairo
Egypt	Assiut Faculty of Medicine	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of patients with malignant masses	sensitivity of the magnetic resonance spectroscopy in diagnosis of brain malignant masses	1 hour