Phase I Study of Fractionated Stereotactic Radiation Therapy

Status Recruiting

Clinical Trial Summary

There is a lack of prospective trial data and consensus guidelines describing the use of Fractionated Stereotactic Radiation Therapy (FSRT) in the treatment of brain metastases. There has been no prospective dose escalation study performed to date to determine the maximum tolerated dose (MTD) in patients treated with FSRT. Prescription doses in the series described above ranged from 18 Gy to 42 Gy, delivered in 3 to 12 fractions. The results of this study will be used to plan future Phase II/III studies to determine the efficacy of different dose fractionation schedules of FSRT. We thus propose a phase I study to determine the feasibility and safety of FSRT in patients with brain metastases.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03726359
Study type	Interventional
Source	Albert Einstein College of Medicine
Contact	Alyssa Asaro, BA
Phone	718-920-5636
Email	aasaro@montefiore.org
Status	Recruiting
Phase	Phase 1
Start date	December 25, 2017
Completion date	May 2027

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