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Clinical Trial Summary

This phase II trial is studying how well pemetrexed disodium works in treating patients with Lung Adenocarcinoma With Brain Metastases


Clinical Trial Description

- Determine the 6-month progression-free survival rate in patients with Lung Adenocarcinoma With Brain Metastases treated with pemetrexed disodium.

- Determine the time to progression in patients with Lung Adenocarcinoma With Brain Metastases treated with pemetrexed disodium.

Secondary

- Determine the radiographic response in patients with Lung Adenocarcinoma With Brain Metastases treated with pemetrexed disodium.

- Determine the time to response in patients treated with this drug.

- Determine the duration of response in patients treated with this drug.

- Determine the overall survival of patients treated with this drug.

- Collect safety data on patients with intracranial tumors treated with this drug.

OUTLINE: Patients receive pemetrexed disodium IV over 10 minutes on day 1. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed periodically. PROJECTED ACCRUAL: A total of 25 patients will be accrued for this study. ;


Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02284490
Study type Interventional
Source Shandong Cancer Hospital and Institute
Contact Yong Wang, M.D
Phone +6813365318361
Email doctorwy@163.com
Status Not yet recruiting
Phase Phase 2
Start date November 2014
Completion date November 2017

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