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Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis — ITIRR  

Brain Metastases, Adult Clinical Trial

Official title:
Differentiation Between Radionecrosis and Tumor Recurrence for Post-stereotactic Radiosurgery Follow-up by Pharmacokinetic Analyses in Perfusion MRI and Positron Emission Tomography

Clinical Trial Summary

During gamma scalpel treatment of brain tumors and metastases, a follow-up magnetic resonance imaging (MRI) scan is performed. The radiologist who reviews the MRI assesses whether there is an increase in signal at the tumor site. This increase potentially indicates that the treatment was not effective. However, in 25% of cases (one in four people), this signal enhancement is not due to ineffective treatment, but to inflammation (swelling/damage) and tissue death around the tumor. This is why when an increase in signal is detected, additional follow-up is essential. The standard additional follow-up has an accuracy of about 83%. This is an observational study on patients with brain metastatis comparing MRI alone or combined to PET-FET to improve accuracy of diagnosis of metastasis recurrence.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05095766
Study type Observational
Source Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Contact
Status Active, not recruiting
Phase
Start date November 23, 2017
Completion date November 23, 2024
View Details
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