Clinical Trials Logo
  1. Home
  2. Brain Edema
  3. NCT04834453
  4. Details
NCT04834453 Clinical Trial

Correlation of Trans Cranial Doppler Ultrasound and CT Scan in Monitoring of Posttraumatic Brain Edema

Brain Edema Clinical Trial

Official title:
Correlation of Trans Cranial Doppler Ultrasound and CT Scan in Monitoring of Posttraumatic Brain Edema

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04834453
Other study ID # R 75/2021
Secondary ID
Status Completed
Phase
First received
Last updated
Start date April 28, 2021
Est. completion date December 28, 2021

Study information
Verified date July 2022
Source Ain Shams University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The most common tool for diagnosis and follow up of cerebral edema in ICU is brain CT scan that necessitate patient transportation with risk of hemodynamic instability, and exposure to radiation. Transcranial Doppler (TCD) sonography allows true and rapid imaging of blood flow velocities of intracranial vessels. Transcranial Doppler sonography provides noninvasive evaluation of intracranial pressure by its characteristic wave patterns

Recruitment information / eligibility
Status Completed
Enrollment 32
Est. completion date December 28, 2021
Est. primary completion date November 10, 2021
Accepts healthy volunteers
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - isolated blunt Traumatic Brain Injury - age 18-60 years Exclusion Criteria: - Pregnancy - Intracerebral hemorrhage - Patients whose blood flow velocities could not be obtained from Trans temporal acoustic bone windows.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• transcranial ultrasound
- Transcranial Doppler sonography will be performed with the patients in the supine position., using low frequency probe of 2 MHz will be placed on temporal bone- will be performed daily

Locations
Country Name City State
Egypt Ain Shams University Cairo

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary the correlation between CCT scans score and Pulsatility Index of each patient 7 days
See also
  Status Clinical Trial Phase
Completed NCT00409058 - Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI N/A
Completed NCT03323580 - Effects of Intraoperative GDFT on the Postoperative Brain Edema N/A
Completed NCT02368366 - Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI N/A
Not yet recruiting NCT04623307 - Non-contact DCS-Speckle Multi-parameter Imaging for Neurological Diseases
Completed NCT00088166 - XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors Phase 3
Completed NCT04311359 - A Pharmacovigilance Study of Brain Oedema
Completed NCT03957837 - Optical Nerve Sheath Changes During Head Down Laparoscopy
Completed NCT02701582 - Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients N/A
Not yet recruiting NCT06307743 - Rapid Local Ischemic Postconditioning in Acute Ischemic Stroke N/A
Completed NCT03573999 - Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation Phase 4
Terminated NCT01369121 - Tolerability Study of Xerecept® in Pediatric Patients Phase 1/Phase 2
Completed NCT05070182 - Resting Energy Needs in Brain Dead Patients (reSting EneRgy nEeds iN brAin DEad Patients)
Completed NCT00226655 - An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies Phase 3
Terminated NCT02320955 - Swiss Prospective Autologous Bone Flap Resorption Study
Completed NCT02037815 - Correlation of Measured and Calculated Serum Osmolality During Hyperosmolar Drugs Infusion in Patients After Craniotomy Phase 4
Completed NCT02594137 - A Comparison Between Two Techniques for Performing Decompressive Craniectomy N/A
Withdrawn NCT00226668 - XERECEPT® (hCRF) for Primary Glioma Patients Requiring Dexamethasone to Treat Peritumoral Brain Edema Phase 3
Terminated NCT01054404 - Furosemide vs Placebo for Brain Relaxation N/A
Recruiting NCT05622461 - Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery N/A
Completed NCT06327737 - Diabetic Ketoacidosis Diagnosis and Management