Brachial Plexus Injury Clinical Trial
Official title:
Enhancing Functional Hand Recovery Through Nerve Reconstruction in Total Brachial Plexus Birth Injury
NCT number | NCT06313658 |
Other study ID # | Total BPBI |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | March 15, 2024 |
Est. completion date | March 15, 2025 |
Interpreting the published outcomes of hand function in total BPBI is confounded by a lack of clear documentation regarding detailed surgical findings and management strategies. Investigators have followed a well-defined protocol for surgical reconstruction with the primary objective being reinnervation of the lower trunk using the best available root. In this paper, Investigators outline the details of the strategy and provide a comprehensive analysis of the nerve reconstruction techniques and the resulting functional outcomes.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | March 15, 2025 |
Est. primary completion date | March 15, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Patients Who underwent brachial plexus exploration and reconstruction for total OBPP. who have reached at least four years of follow-up Exclusion Criteria: - Excluding children who had selective distal neurotization for restoration of specific functions without brachial plexus exploration or who had secondary procedures to the hand. |
Country | Name | City | State |
---|---|---|---|
Egypt | Assiut University Hospitals | Assiut |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Egypt,
Al-Qattan MM. Assessment of the motor power in older children with obstetric brachial plexus palsy. J Hand Surg Br. 2003 Feb;28(1):46-9. doi: 10.1054/jhsb.2002.0831. — View Citation
Borschel GH, Clarke HM. Obstetrical brachial plexus palsy. Plast Reconstr Surg. 2009 Jul;124(1 Suppl):144e-155e. doi: 10.1097/PRS.0b013e3181a80798. — View Citation
Haerle M, Gilbert A. Management of complete obstetric brachial plexus lesions. J Pediatr Orthop. 2004 Mar-Apr;24(2):194-200. doi: 10.1097/00004694-200403000-00012. — View Citation
Pondaag W, Malessy MJ. Recovery of hand function following nerve grafting and transfer in obstetric brachial plexus lesions. J Neurosurg. 2006 Jul;105(1 Suppl):33-40. doi: 10.3171/ped.2006.105.1.33. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Active Movement Scale (AMS) | All patients included in the study were evaluated using the Active Movement Scale (AMS), which grades upper extremity movements from 0 to 7. Scores of 6 or 7 would be considered successful in demonstrating functionally useful movement; this is a 50% and full range of movement against gravity, respectively.Attention was focused on sex movements primarily involving hand function including wrist, finger, and thumb flexion and extension. | 1 year | |
Secondary | Al-Qattan pronation/Supination score | Separate assessments were performed of forearm pronation/supination as described by Al-Qattan | 1 year | |
Secondary | Raimondi hand score | Global hand function was assessed using the Raimondi scale; a score of 3 or more indicate a useful functional recovery | 1 year |
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT05859178 -
Exercise Training for Brachial Plexus Injury Following Nerve Transfer
|
Phase 2 | |
Completed |
NCT05575674 -
Retrospective Study on Myoelectric Elbow-Wrist-Hand Orthosis User Outcomes
|
||
Enrolling by invitation |
NCT06437990 -
Arteriovenous Loop Graft for Free Functional Gracilis Transfer in Brachial Plexus Surgery
|
N/A | |
Completed |
NCT01393444 -
ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis
|
N/A | |
Active, not recruiting |
NCT04900896 -
Outcome Measures Study on an Adult Myoelectric Elbow-Wrist-Hand Orthosis
|
||
Terminated |
NCT01297439 -
New Prophylactic Maneuver: the "Pushing" Maneuver, Aiming to Reduce the Risk for Shoulder Dystocia
|
N/A | |
Completed |
NCT06237270 -
External Validation Study for Risk Prediction Model for Unsuccessful Elbow Flexion Recovery After Nerve Transfer Surgery in Patients With Brachial Plexus Injury
|
||
Not yet recruiting |
NCT05810077 -
Feasibility of Brachial Plexus Ultrasound in Evaluation of Patients With Brachial Plexus Injuries
|
||
Not yet recruiting |
NCT04959058 -
EVALUATION OF BRACHIAL PLEXUS IN DIFFERENT ARM POSITION
|
N/A | |
Recruiting |
NCT04939233 -
Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries
|
N/A | |
Recruiting |
NCT00755586 -
Stem Cell Therapy to Improve the Muscle Function of Patients With Partly Denervated Muscles of the Arm
|
Phase 1/Phase 2 | |
Completed |
NCT03377712 -
Surgical Repercussions in Respiratory System in Patients With Post-Traumatic Brachial Plexus Injuries: A Prospective Cohort Study
|
||
Completed |
NCT03409536 -
Somatosensory Evoked Potential (SSEP) Monitoring for Brachial Plexus Injury
|
||
Completed |
NCT03162393 -
The Surgical Treatment of Total Brachial Plexus Avulsion Injury-A Retrospective Study of 73 Patients
|
N/A | |
Recruiting |
NCT04733599 -
Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury
|
||
Enrolling by invitation |
NCT04933149 -
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
|
Phase 4 | |
Recruiting |
NCT01894802 -
Cortical Recording and Stimulating Array Brain-Machine Interface
|
N/A | |
Completed |
NCT02711774 -
Changes in Optic Nerve Sheath Diameter in Response to Various Levels of End Tidal Carbon Dioxide Levels
|
N/A | |
Recruiting |
NCT05693038 -
Brachial Plexus Injury After Prone Positioning
|
||
Withdrawn |
NCT01334632 -
Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
|
N/A |