Clinical Trials Logo
  1. Home
  2. Bowel Obstruction
  3. NCT01507220

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 — IMPROVE-Open  

Bowel Obstruction Clinical Trial

Official title:
A Pain Relief Trial Utilizing the Infiltration of a Multivesicular Liposome Formulation Of Bupivacaine, EXPAREL®: A Phase 4 Health Economic Trial in Adult Patients Undergoing Open Colectomy

Clinical Trial Summary

This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome extended-release injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL therefore possibly reducing total hospitalization costs.

Clinical Trial Description

This is a phase 4, prospective, sequential, open-label study designed to evaluate the efficacy, safety, and health economic benefits of intraoperative local wound infiltration with EXPAREL (bupivacaine liposome extended-release injectable suspension) compared with postsurgical administration of standardized intravenous (IV) morphine sulfate for postsurgical analgesia in adult patients undergoing open colectomy with general anesthesia. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01507220
Study type Interventional
Source Pacira Pharmaceuticals, Inc
Contact
Status Terminated
Phase Phase 4
Start date March 2012
Completion date July 2012
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05442164 - Effect of Implementation of the Danish Emergency Surgery (DANAKIR) Support Network on Post-discharge Outcomes After Major Emergency Abdominal Surgery
Recruiting NCT04675606 - Implementing a Low Fiber Diet vs. Regular Diet in Postoperative Colorectal Patients With Ileostomies N/A
Completed NCT04613063 - Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome
Recruiting NCT06089551 - Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery Phase 4
Completed NCT03202576 - Nasogastric Tube Securement Comparison Study N/A
Terminated NCT01507233 - A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 Phase 4
Completed NCT01040364 - Internal Hernias After Laparoscopic Gastric Bypass N/A
Not yet recruiting NCT04848415 - Diagnostic Performance of Point of Care Ultrasound to Identify Intestinal Obstruction
Completed NCT04898842 - Feasibility Study of a 4 Stage Bowel Obstruction Cancer Diet N/A
Not yet recruiting NCT05253222 - Methodology and Clinical Value of RIT in Intestinal Obstructive Diseases Mediated by Colonic TET N/A
Recruiting NCT04709445 - Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses N/A
Recruiting NCT04539028 - Emergency General Surgery for Non-trauma
Terminated NCT01911793 - Stoma Tube Decompression and Postoperative Ileus After Major Colorectal Surgery N/A
Recruiting NCT03150992 - EDMONd - Elemental Diet in Bowel Obstruction N/A
Terminated NCT02116881 - Incisional Hernia and Adhesion-Related Bowel Obstruction N/A
Recruiting NCT00164879 - Endolaparoscopic Versus Immediate Surgery for Obstructing Colorectal Cancers Phase 3
Completed NCT03350022 - Sham Feeding Post-operative Infants N/A
Not yet recruiting NCT03593252 - Bowel Preparation in Elective Pediatric Colorectal Surgery N/A
Completed NCT05753709 - Conventional Hand Sewn End-To-End Anastomosis Versus Side-To-Side Anastomosis for Stoma Reversal: A Prospective Study N/A
Enrolling by invitation NCT05085353 - Fetal Outcomes Among Pregnant Emergency General Surgery Patients