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NCT05357521 Clinical Trial

Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder

Borderline Personality Disorder Clinical Trial

— OXT-CORT-BPD  

Official title:
Feasibility and Preliminary Data on the Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05357521
Other study ID # 2002-00067
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 1, 2022
Est. completion date April 30, 2022

Study information
Verified date June 2022
Source University of Geneva, Switzerland
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.

Description:

The investigators will recruit 10 female patients with borderline personnality disorder and 10 controls with no psychiatric diagnosis, aged between 18 and 25 years old. salivary cortisol daily curve ( 6 measures during the day) will be measured in participant's naturalistic environnement, together with salivary oxytocin. In addition, salivary oxytocin and cortisol will be measured during a psychosocial stress task and recovery.

Recruitment information / eligibility
Status Completed
Enrollment 19
Est. completion date April 30, 2022
Est. primary completion date April 30, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 25 Years
Eligibility Inclusion Criteria: - Borderline personality disorder-DSM V Exclusion Criteria: - Schizophrenia

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• stress test
TSST- psychosocial stress test

Locations
Country Name City State
Switzerland Young Adult Psychiatric Unit Geneva

Sponsors (1)
Lead Sponsor Collaborator
University of Geneva, Switzerland

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Salivary cortisol salivary cortisol measured with salivettes (swabs) Baseline
Primary Salivary cortisol salivary cortisol measured with salivettes (swabs) Change in one day (circadian cortisol with 6 measures within one day
Primary Salivary cortisol salivary cortisol measured with salivettes (swabs) Change during experimental task (up to 2 hours)
Primary Salivary oxytocin salivary oxytocin measured with salivettes (swabs) Baseline
Primary Salivary oxytocin salivary oxytocin measured with salivettes (swabs) Two measures within one day
Primary Salivary oxytocin salivary oxytocin measured with salivettes (swabs) Change during experimental task (up to 2 hours)
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