Central Meditation and Imagery Therapy for Augmentation of Borderline Personality Disorder Treatment

Borderline Personality Disorder Clinical Trial

Official title:

Pilot Study of Central Meditation and Imagery Therapy for Borderline Personality Disorder

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02125942
• Other study ID #: CMIT1044
• Status: Completed
• Phase: N/A
• Start date: April 2014
• Est. completion date: September 2015

Study information

• Verified date: January 2021
• Source: University of California, San Francisco
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Borderline personality disorder is a severe psychiatric disorder marked by emotional instability, difficulty with interpersonal relationships, and self-harming behaviors. Despite receiving psychotherapy for borderline personality disorder, studies show that patient recovery is slow, and there is a high rate of self injury and suicide attempts early in treatment. There is thus a clear need to provide therapies to augment psychotherapy. We will conduct a pilot trial to determine whether a 6-week Central Meditation and Imagery Therapy (CMIT) is feasible for subjects with borderline personality disorder to undergo when added on to psychotherapy treatment. CMIT is a non-validated therapy that combines principles of mindfulness with meditation techniques and guided imagery. Sessions led by a trained clinician in a group setting once a week, and participants are asked to complete daily home practice. The trial will involve 16 participants, all currently undergoing psychotherapy for borderline personality disorder. Participants will be randomly assigned to either a CMIT group that lasts 6 weeks, or a wait list group. Those in the wait list group will be able to receive CMIT after 6 weeks. All participants will continue to receive psychotherapy throughout the trial. During the trial, we will also obtain preliminary data to help understand whether CMIT may result in psychological benefits for participants. This will include measuring the pulse in order to determine variation in beat to beat intervals of the heart during psychological tests, and filling out questionnaires before and after participation in CMIT.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Est. completion date: September 2015
• Est. primary completion date: September 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Meeting the diagnostic criteria for BPD according to DSM-IV criteria
• Meeting the diagnostic criteria for BPD based on the Diagnostic Interview for Borderline - Revised
• Currently receiving psychotherapy.
• English language proficiency to understand written and oral communication

Exclusion Criteria:

• Active suicidality or suicidal intent as identified on the Columbia Suicide Severity Rating Scale
• Suicide attempt within the past month

Related Conditions & MeSH terms

• Borderline Personality Disorder
• Disease
• Personality Disorders

Intervention

Behavioral:
• Central Meditation and Imagery Therapy
mindfulness, guided imagery, meditation

Locations

Country	Name	City	State
United States	University of California, Los Angeles	Los Angeles	California

Sponsors (1)

Lead Sponsor	Collaborator
University of California, San Francisco

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Heart rate variability	Resting heart rate variability	6 weeks
Primary	Borderline Symptoms	Borderline Symptom List	6 weeks
Secondary	Depression	Quick Inventory of Depressive Symptoms	6 weeks
Secondary	Anxiety	Trait Anxiety Inventory	6 weeks
Secondary	Positive Affect	Positive and Negative Affect Scale	6 weeks