Borderline Personality Disorder Clinical Trial
Official title:
Mentalization-Based Treatment in Groups for Adolescents With Borderline Personality Disorder (BPD) or Subthreshold BPD Versus Treatment As Usual - the M-GAB Randomized Controlled Trial
Background: Although it is now possible to diagnose Borderline Personality Disorder (BPD) in
adolescents younger than 18 years according to the Diagnostic and Statistical Manual of
Mental Disorders, 5th edition (DSM-V), and studies indicates that BPD can be reliably
diagnosed in adolescence, only a few evidence based treatment programmes for adolescent BPD
exists. Mentalization-based treatment (MBT), including group psychotherapy, has repeatedly
shown to be effective in treating adult BPD, but in the case of adolescents, only individual
MBT have been tested and found to be effective.
Aims/hypotheses: We will test whether group based MBT (MBT-G), including an introductory
programme for patients (MBT-I) and their parents (MBT-P) is more effective than Treatment As
Usual (TAU) in treating adolescents with BPD or subthreshold BPD.
Methods/Design: 112 patients referred to child and adolescent psychiatric clinics in Region
Zealand will be randomized to either MBT or TAU. Inclusion criteria: Meeting DSM-V
BPD-criteria at the threshold (five criteria) or sub threshold level (4 criteria). Follow-up
will be at three and 12 months.
Discussion: Early intervention is especially important in relation to personality
psychopathology and has long-term benefits for patients, their families and society. In
addition to being cost effective, using the group modality in the treatment of BPD may have
several advantages. This is the first Randomized Controlled Trial (RCT) to test the
effectiveness of MBT in groups for adolescents.
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