Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT03007069
Other study ID # CairoMPM-ABG
Secondary ID
Status Not yet recruiting
Phase N/A
First received December 25, 2016
Last updated December 30, 2016
Start date January 2017
Est. completion date December 2017

Study information

Verified date December 2016
Source Cairo University
Contact n/a
Is FDA regulated No
Health authority Egypt: Ministry of Higher Education
Study type Interventional

Clinical Trial Summary

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards.


Description:

To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.

-PICO-

Population (P): Patients with defective maxillary alveolar ridge requiring implant insertion.

Intervention (I): Ridge augmentation with MPM.

Comparator (C): Autogenous bone graft.

Outcome (O): Patient satisfaction - Implant stability.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 20
Est. completion date December 2017
Est. primary completion date September 2017
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria:

1. Medically free patients.

2. Evaluated bone height on CBCT to be (0-4 mm buccal bone dehiscence) and width (not less than 4.5 mm)

3. Patients with Anterior maxillary defective partially edentulous ridge.

4. Age between 18 and 40 years.

5. Both sexes.

6. Patients physically able to tolerate surgical and restorative procedures.

7. Patients with an opposing tooth to the pre-implant site.

8. Good oral hygiene.

9. Highly motivated patients.

Exclusion Criteria:

1. Patients allergic to local anesthetic agent.

2. Pregnant or lactating females.

3. Presence of any pathosis in the pre-implant site.

4. Presence of any mucosal disease.

5. Presence of parafunctional habits.

6. History of oral radiotherapy.

7. History of prolonged steroids use.

8. Psychological disorders.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Other:
Mineralized plasmatic matrix (MPM).
By using venoud blood from the patient, together with bone graft, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM, for 10 minutes , Which will result if sticky bone graft consistency after mixing.
Autogenous bone graft (gold standard).
Exposed implant threads are to be covered with autogenous bone and collagen membrane.

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Cairo University

Outcome

Type Measure Description Time frame Safety issue
Primary Patient Satisfaction regarding esthetic results , outcome will be measure using questionnaire. 5 months Yes
Secondary Stability of dental implants , this will be measured using Ostell device in ISQ units. 5 months. Yes
See also
  Status Clinical Trial Phase
Recruiting NCT04073654 - SA Versus SOI Surfaces for Single Implant-supported Crown N/A
Recruiting NCT06374342 - BONE SUBSTITUTES OUTCOMES
Not yet recruiting NCT04345250 - Bone Response to Exercise and Energy Restriction in Young Adults N/A
Completed NCT05533502 - Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults N/A
Completed NCT04279392 - Healthy Body, Healthy Bones After Bariatric Surgery Trial Phase 1/Phase 2
Recruiting NCT04548258 - Bone Changes Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast One N/A
Withdrawn NCT04331028 - Effect of Shock-wave Therapy on the Resorption and Bone Formation in Maxillary Postextraction Sockets N/A
Completed NCT06383117 - Understanding Effects of Calcium on the Gut-Bone Axis N/A
Recruiting NCT06334159 - Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes N/A
Completed NCT03888339 - Influence of Abutment Shape on Peri-implant Marginal Bone Loss N/A
Completed NCT03026894 - Association of Force Distribution and Bone Resorption N/A
Completed NCT02470611 - Sodium Alendronate in Non Surgical Periodontal Therapy Phase 4
Completed NCT00297830 - Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation Phase 2/Phase 3
Recruiting NCT03431766 - 0.2% Chx Gel vs Implant Bacterial Contamination N/A
Recruiting NCT04141215 - Allogeneic Bone Paste Versus Allogeneic Bone Powder N/A
Recruiting NCT05018130 - Bio-Integrative Versus Metallic Screws for Calcaneus Osteotomies N/A
Completed NCT04790019 - The Effects of Low Energy Availability and High Impact Jumping on Markers of Bone (re)Modelling in Females N/A
Recruiting NCT03889587 - Innervation of Vascularized Iliac Transplant Avoids Resorption in Jaw Bone Reconstruction N/A
Completed NCT05804604 - Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures
Terminated NCT03089619 - Alveolar Management Following Teeth Extraction Phase 4