Bone Neoplasm Clinical Trial
Official title:
Rehabilitation Treatment and Early Recovery After "Wedge Resection" for Pulmonary Metastasis Secondary to Bone Cancer: an Observational Study.
After "wedge resection" surgery, the physiotherapy programs proposed in the literature are heterogeneous and there are few data on the outcomes of such treatments in an oncological population for bone cancer. The aim of the study is to describe the early rehabilitation process after wedge resection surgery secondary to bone tumor pulmonary mestasasis, highlightining the possible functional recovery in the short and medium term after surgery and indentifying the possible prognostic factors.
In Italy, the incidence of primary bone tumors is around 0.8-1 case per 100,000 inhabitants, therefore an estimated 500 new cases of primary malignant bone tumors are estimated each year, affecting more frequently in children and young people. The presence of pulmonary metastasis occurs in 30% of the population with bone cancer and is the most common site of metastasis. Where possible, the elective treatment of lung metastases is ablative surgery and the wedge resection technique is also commonly used in the event of repeated metastasis over time. Pulmonary wedge resection surgery does not follow the anatomical limits of the lung but it is customized according to the metastatic area to be removed, thus differentiating itself from lobectomies and other thoracotomy surgical techniques. The trend of vital capacity (CV) and forced expiratory volume in 1s (FEV1), after wedge resection surgery, significantly decrease at 3 months compared to the preoperative evaluation, while at 12 months the CV returns to values close to the preoperative ones and FEV1 remains significantly lower. Rehabilitation treatment is part of the multidisciplinary approach for this type of patient in order to prevent post-surgical respiratory complications (PPC) and shoulder girdle dysfunctions, in the treatment of pain and in the recovery of respiratory volumes. Several authors, describing the physiotherapy treatment techniques, include breathing exercises (Active Cycle Breathing Techniques), early mobilization exercises for the lower limbs and the use of volume incentives. The physiotherapy treatment programs proposed in the literature are heterogeneous and there are no data on the feasibility of such treatments in an oncological population for bone cancer. Patients are enrolled consecutively in a ward of an italian hospital specialized in bone tumor surgery. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03072186 -
Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery
|
N/A | |
| Not yet recruiting |
NCT06376539 -
Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.
|
||
| Recruiting |
NCT03129672 -
Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle
|
||
| Not yet recruiting |
NCT03106675 -
MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases
|
N/A | |
| Completed |
NCT04884048 -
Multicentric Bone Tumor Imaging Report and Data System
|
||
| Completed |
NCT00841152 -
Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute
|
||
| Recruiting |
NCT04307914 -
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
|
N/A | |
| Withdrawn |
NCT00478270 -
A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease.
|
Phase 2 | |
| Recruiting |
NCT04394052 -
Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II
|
||
| Terminated |
NCT00099203 -
A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease
|
Phase 3 | |
| Completed |
NCT05881343 -
Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery
|
||
| Active, not recruiting |
NCT03678883 -
9-ING-41 in Patients With Advanced Cancers
|
Phase 2 | |
| Recruiting |
NCT03442465 -
Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
|
||
| Terminated |
NCT00099177 -
A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain
|
Phase 3 | |
| Completed |
NCT04074291 -
Cross Cultural Validation of the Italian Version of the Bt-DUX
|
||
| Completed |
NCT04310410 -
Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis
|
Phase 1/Phase 2 |