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Clinical Trial Summary

Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.


Clinical Trial Description

During cyst enucleation , There's resultant decrease in bone density especially in large defects .Therefore, it may be needed for a bone grafts and bone regenerative materials to improve quality of bone .The rationale is to evaluate hyaluronic acid with hydroxyapatite as a bone quality improvement material following cyst enucleation, which would provide significant bone regeneration. Hydroxyapatite is inorganic component of bone tissue used as bone graft, scaffolds, filler and cement for repair and regeneration of bone defect , and it is stimulate bone remodeling by generating surface active moieties or cell signaling process while Hyaluronic acid and it's derivatives has been widely used for bone regeneration and it has a good potential for osteogenesis and mineralization ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05957926
Study type Interventional
Source Cairo University
Contact Enas Eldaour, BSc.
Phone 01016676513
Email enas.fadel@dentistry.cu.edu.eg
Status Not yet recruiting
Phase N/A
Start date October 1, 2023
Completion date January 1, 2025

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