Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant

Bone Loss Clinical Trial

Official title:

The Effect of Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant in the Esthetic Zone

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04298294
• Other study ID #: Bassant Mohye
• Status: Completed
• Phase: N/A
• Start date: February 16, 2018
• Est. completion date: December 1, 2019

Study information

• Verified date: March 2020
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone

Description:

Grouping the samples: (sixteen patients was recruited from the outpatient clinic of Oral Medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dentistry, Ain Shams University).

The sixteen patients assigned to group 1 or group 2 will be randomly allocated using flip of a coin into one of the 2 treatment modalities.

Primary objective:

Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.

Secondary objective:

Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: December 1, 2019
• Est. primary completion date: October 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

• Healthy adult patient.

• Age from 20-50 years old

• Patients must be free of any systemic disease which could influence the surgical procedure.

• Tooth involved in the esthetic zone.

• Sufficient hard and soft tissue volume in vertical and buccolingual 6. Natural teeth adjacent to the involved tooth were required to be free from infection.

• Controlled oral hygiene.

• Indication for tooth extraction included;

• Endodontic failures

• Untreatable caries? Non- restorable teeth

• Vertical root fracture

• Remaining roots

• The decision to proceed with the implant placement was made after tooth extraction and probing of the extraction socket which revealed:

• The presence of intact facial bone.

• Compliance with all requirements in the study and signing the informed consent.

Exclusion Criteria:

• Patient had surgeries in the same site during the last 6 months prior to the surgery.

• Severe vertical bone loss (socket type lll or type lV).

• Presence of acute dento-alveolar infection or periodontal affected of involved tooth.

• Pregnant and lactating females.

• Smokers.

Related Conditions & MeSH terms

• Bone Loss

Intervention

Other:
• injectable platelet rich fibrin
biologic activator

Locations

Country	Name	City	State
Egypt	Bassant Mohye	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.	density, vertical and horizontal assessment of labial plate	6 months follow up
Primary	Radiographic analysis	vertical assessment of labial plate	6 months follow up
Primary	Radiographic analysis	density of labial plate	6 months follow up
Secondary	Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant	pink esthetic score	6 months follow up