CGF Influence on Post-operative Complications.

Bone Loss Clinical Trial

Official title:

The Influence of Concentrated Growth Factors (CGF) Application on Post-operative Complications.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03992573
• Other study ID #: 0001
• Status: Recruiting
• Phase: N/A
• Start date: October 1, 2017
• Est. completion date: June 1, 2020

Study information

• Verified date: June 2019
• Source: Medical Universtity of Lodz
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to evaluate the influence of CGF application into post-operative soft tissue and bone defects on post-operative complications and wound healing.

Description:

The research was conducted in twenty patients with symmetric single tooth qualified to extraction. On one side of dental arch, post-operative region was field with CGF material, while on the other side it was left to normal healing. In both cases pain, swelling, alveolar osteitis, antibiotics and analgesics intake in post-operative period were evaluated in the first, fourth and seventh day after surgery. Wound healing was assessed seven and thirty days after extraction.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: June 1, 2020
• Est. primary completion date: March 1, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• no known medical history of abnormal platelet counts,

• patients with symmetric teeth qualified for extraction,

Exclusion Criteria:

• systemic diseases,

• pregnancy,

• lactation,

• drugs known to affect the number or function of platelets,

• abnormal platelet counts

Related Conditions & MeSH terms

• Bone Loss
• CGF
• Post-operative Wound Healing
• Postoperative Complications
• Surgical Wound

Intervention

Procedure:
• CGF application
CGF application into post-operative soft tissue and bone defects

Locations

Country	Name	City	State
Poland	Department of Oral Surgery	Lodz

Sponsors (1)

Lead Sponsor	Collaborator
Medical Universtity of Lodz

Country where clinical trial is conducted

Poland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intensity of pain vs. CGF application	In order to evaluate the relationship between intensity of pain after surfery and filling the alveolus with platelet-rich plasma, , NRS (Numeric Rating Scale) pain scale is used.; NRS scale, ranges from 0 to 10; where 0 refers to no pain and 10 refers to most severe pain.	24 hours
Secondary	Occurrence of swelling	The presence of swelling was evaluated using zero one system.	24 hours