Interventional Radiology in Bony Lesions

Status Not yet recruiting

Clinical Trial Summary

To explore the capability of the interventional radiology techniques in management of the painful bony lesions .

Clinical Trial Description

Bone tumors may present as incidental findings, with pain or loss of function, or as fractures [1]. Interventional Radiology (IR) has experienced an exponential growth in recent years. Technological advances of the last decades have made it possible to use new treatments on a larger scale, with good results in terms of safety and effectiveness[2] . Today, IR represents a minimally invasive option of treatment for benign bony lesions (osteoid osteoma [OO], osteoblastoma, periosteal chondroma, etc.) and for palliation of metastases involving bone and soft-tissue sites beyond the liver and lung in an always-increasing number of cases [3][4]. The aim of minimally-invasive ablation treatment is addressing the biological pain due to the stretching and irritation of the periosteum secondary to tumor growth and due to osteoclast-mediated bone resorption with the release of neurostimulating cytokines. The purpose of cementoplasty is to treat the mechanical pain for the instability from pathologic microfractures [5] Radiofrequency ablation (RFA) and cementoplasty are safe, feasible, and promising clinical option for the management of painful bony tumors that are challenging for their morphology and location [6]. Also , there is a broad range of indications for transarterial embolization (TAE) in primary or metastatic bone tumors: to reduce operative haemorrhagic risks, to simplify or allow more definitive surgery, or in the context of pain palliation, fever, bleeding, or hypercalcemic and other rheological factors[1]. ;

Study Design

Related Conditions & MeSH terms

Bone Lesion

Clinical Trial Details

NCT number	NCT05738941
Study type	Observational
Source	Assiut University
Contact	Mostafa Othman, PHD
Phone	01000684012
Email	hashemradiol@aun.edu.eg
Status	Not yet recruiting
Phase
Start date	March 1, 2025
Completion date	April 30, 2025

View Details

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