Clinical Trials Logo
  1. Home
  2. Bone Diseases
  3. NCT03905174

Massive Implants the Next Generation — MING  

Bone Diseases Clinical Trial

Official title:
A Randomised, Single Blind Study Assessing Radiological Outcomes for Massive Segmental Femoral Replacements Using Either Porous Collar or Porous Collar With HA or Porous Collar With HA and Autologous Stem Cells

Clinical Trial Summary

The study will review the use of massive segmental replacements in the femur, which have a porous collar with and without HA, and autologous stem cell augment. This is a randomised controlled trial.

Clinical Trial Description

The current surgical treatment of bone cancer patients and revision limb salvage requires usage of massive endoprosthetic bone implants. The incidence of aseptic loosening is a major cause of prosthesis failure in these patients, exploring ways to reduce such failures would allow extending longevity of massive implants in a relatively young population. Current published literature stipulates that osteointegration could improve longevity of massive implants. Evidence suggests that usage of osteointegrated hydroxyapatite (HA) coated collar would reduce the incidence of aseptic loosening around the cemented intramedullary stem in distal femoral bone prosthesis ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03905174
Study type Interventional
Source Royal National Orthopaedic Hospital NHS Trust
Contact Panos Gikas, PhD FRCS
Phone 02089092300
Email rnoh.research@nhs.net
Status Recruiting
Phase N/A
Start date September 20, 2018
Completion date December 31, 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT03672513 - Short-term Supplementation, Bone Turnover and Antioxidant Status in Menopause N/A
Completed NCT00070681 - Outcomes of Sleep Disorders in Older Men Phase 3
Completed NCT03050203 - Custom Pack in Spine Surgery N/A
Completed NCT00000466 - Postmenopausal Estrogen/Progestin Interventions (PEPI) Phase 3
Recruiting NCT03904914 - Thumb Ossification Composite Index (TOCI) to Predict Skeletal Maturity and Curve Progression in AIS
Completed NCT04608708 - 3D Analysis of Cemento-Osseous Lesions
Completed NCT02252679 - Study of the Diagnostic Value of Stable Calcium Isotope Profiling in Bone and Calcium Disorders
Completed NCT03633032 - Radiation-free Bone Imaging UTE MRI in Healthy and Diseased Patients N/A
Recruiting NCT03431727 - Acromegaly - Before and After Treatment
Completed NCT03072186 - Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery N/A
Completed NCT03438123 - Data Collection Study for the Spectrum Dynamics Multi-purpose CZT SPECT Camera N/A
Recruiting NCT06116071 - Biomarkers Related to Bone in Pediatric Gaucher Disease
Not yet recruiting NCT05840003 - Image Quality: Ultra-Low Dose Scanner Versus Standard Dose Conventional Scanner for Thoraco-abdominopelvic Scans N/A
Withdrawn NCT04955652 - Evaluation of Alerts in Promoting Bone Densitometry Scans N/A
Recruiting NCT00270608 - How Does Early Age Life Style Affect Bone Strength and General Health Parameters at Middle Age? N/A
Active, not recruiting NCT00150163 - Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish Men N/A
Completed NCT00155961 - Odense Androgen Study in the Elderly Phase 1
Terminated NCT03802656 - Vertebral Body Tethering Treatment for Idiopathic Scoliosis N/A
Not yet recruiting NCT05802121 - Akkermansia Muciniphilia and Metabolic Side Effects of ADT Early Phase 1
Recruiting NCT02809781 - A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis Phase 2/Phase 3