Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05527431
Other study ID # FAMSU R 115/ 2022
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 1, 2022
Est. completion date April 1, 2024

Study information

Verified date August 2023
Source Ain Shams University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

to compare high flow nasal cannula against noninvasive ventilation in patients with non-sever blunt chest trauma in improvement of oxygenation, need for intubation and mechanical ventilation within 28 days


Recruitment information / eligibility

Status Completed
Enrollment 120
Est. completion date April 1, 2024
Est. primary completion date January 1, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria: - Age =18 y, - Willing and able to provide written informed consent prior to performing study procedures, - currently hospitalized and requiring medical care for non-sever blunt chest trauma (abbreviated injury severity scale = 2) SpO2 90% or less while breathing 10 L/min. Exclusion Criteria: - Contraindications of noninvasive ventilation (face trauma or surgery, airway obstruction, upper gastrointestinal tract bleeding, disturbed level of consciousness), -smoker - intubation for any cause other than respiratory cause

Study Design


Intervention

Device:
high flow nasal cannula
high flow nasal cannula
noninvasive ventilation
noninvasive ventilation

Locations

Country Name City State
Egypt Ain Shams University hospitals Cairo

Sponsors (1)

Lead Sponsor Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary PaO2/FiO2 ratio mean value of three successive PaO2/FiO2 ratio in mmHg between both groups 3 successive days
Secondary Discomfort score Discomfort related to oxygen delivery devices will be evaluated using a 10- point numeric scale which low number is low discomfort. 3 successive days
See also
  Status Clinical Trial Phase
Completed NCT06236113 - Low Dose Ketamine for Blunt Thoracic Trauma Phase 4
Completed NCT03580187 - Nebulized Morphine in Chest Trauma Patients: A Prospective Study Phase 3
Active, not recruiting NCT01367951 - Treatment of Acute, Unstable Chest Wall Injuries N/A
Not yet recruiting NCT05886946 - Abg in Blunt Chest Trauma
Not yet recruiting NCT06316375 - STUMBL Score as a Risk Stratification Tool for Management of Blunt Chest Trauma Patients