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Autonomic Cardiovascular Control in Response to Blood Volume Reduction in Blood Donors

Blood Loss Clinical Trial

Official title:
Autonomic Cardiovascular Control in Response to Blood Volume Reduction in Blood Donors

Clinical Trial Summary

The function of the autonomic nervous system can be assessed using baroreflex sensitivity (BRS) and heart rate variability (HRV). Decreased HRV has been shown to be predictive of morbidity and mortality in diverse medical conditions such as acute myocardial infarction, aneurysmal subarachnoid haemorrhage, autoimmune diseases, sepsis and surgery. The function of the autonomic nervous system has not yet been investigated in a "pure hypovolemia" model. The aim of the current study is therefore to investigate and describe the function of the autonomic nervous system prior to, during and after reduction of blood volume in healthy blood donors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04499664
Study type Observational
Source Hvidovre University Hospital
Contact
Status Completed
Phase
Start date August 1, 2020
Completion date June 1, 2022
View Details
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