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Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma

Blood Loss Clinical Trial

Official title:
Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma: A Randomized Double Blind Clinical Trial

Clinical Trial Summary

This is a prospective, randomized, double-blind study investigating whether intravenous tranexamic acid has any effect on blood loss during maxillofacial trauma surgery, or the subsequent postoperative sequelae. Intraoperative bleeding and postoperative ecchymosis and edema are objectively rated and complications are noted.

Clinical Trial Description

This is a prospective, randomized, double-blind pilot study investigating whether intravenous tranexamic acid has any effect on blood loss during maxillofacial trauma surgery, or the subsequent postoperative sequelae. Intraoperative bleeding is calculated from anaesthesia chart and recorded in ml. Postoperative ecchymosis and bleeding are recorded as dichotomous events (yes/no) and are subjectively rated by both patient and surgeon on postoperative days 1and 2. Any surgical or postoperative complications are noted. Scores are aggregated for statistical analysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04494126
Study type Interventional
Source College of Medical Sciences Teaching Hospital. Nepal
Contact Ashutosh K Singh, MDS
Phone +9779855082369
Email dr.ashutosh@cmsnepel.edu.np
Status Not yet recruiting
Phase Phase 4
Start date August 15, 2021
Completion date December 15, 2021
View Details
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