Effect of Processed Blueberry on Blood Glucose and Antioxidant Status in Human Adults

Blood Glucose Clinical Trial

Official title:

Effect of Hydro-Thermodynamic (HTD) Processed Blueberries on Postprandial Blood Glucose Control and Antioxidant Status in Human Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04396262
• Other study ID #: 2019-204
• Secondary ID: 2015-102
• Status: Completed
• Phase: N/A
• Start date: November 1, 2015
• Est. completion date: August 31, 2022

Study information

• Verified date: March 2023
• Source: Mount Saint Vincent University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Canada's Food Guide (2007) recommended 7-10 servings of fruits and vegetables per day for a normal adult population. Although fruit juice (125 ml) is considered as one serving of fruits, the consumption of some fruit juices may be limited due to their high amount of sugar. The consumption of sugary drinks can lead to a rapid rise in postprandial glycaemia. Wild blueberries, due to their high level of anthocyanins, may provide multiple health benefits including improved blood glucose control, however, the consumption of fresh berries is limited by their short seasonal availability. Hydro-Thermodynamic (HTD) processing of blueberries allows the processing of whole berries including their skin and seeds into a beverage with the amount of anthocyanins comparable with fresh berries. The objective of the study is to investigate the effect of HTD-processed blueberries on postprandial glycaemia and antioxidant activity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: August 31, 2022
• Est. primary completion date: August 31, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Healthy adults

• Body mass index (BMI) within normal range (18.5-24.9 kg/m2 for adults)

Exclusion Criteria:

• Chronic metabolic diseases or inflammatory conditions

• Smokers

• A medication that influences glucose control or gastrointestinal function

• Known allergies

• Intellectual disabilities

Related Conditions & MeSH terms

• Blood Glucose

Intervention

Other:
• Food-1
HTD-blueberry beverage with white bread.
• Food-2
Sweetened water with white bread as a control.

Locations

Country	Name	City	State
Canada	Mount Saint Vincent University	Halifax	Nova Scotia

Sponsors (1)

Lead Sponsor	Collaborator
Mount Saint Vincent University

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Blood glucose	The concentration of glucose in venous blood after consuming HTD-blueberry beverage with white bread or water control with white bread.	0-120 min
Secondary	Postprandial antioxidant activity in blood	The total antioxidant activity in blood plasma determined using a commercial Antioxidant Assay Kit.	0-120 min