Clinical Trials Logo

Clinical Trial Summary

Immunotherapies have substantially improved the prognosis of patients with haematological malignancies. While clinical trial data suggest durable complete response rates, markers associated with non-response to treatment are still poorly described. The identification of predictive markers using demographic, physiologic, biologic, immunologic data as well as patients' treatment history, might enable the optimization of therapeutic sequences and the reduction of treatment toxicity. This study aim to assess markers of toxicity and response following an immunotherapy in patients with a haematological malignancy using real life data. It will allow the development of clinical and therapeutic benchmarks to guide medical decisions in relation to the therapeutic strategies to be implemented for patients benefiting from real-life conditions, in addition to the results obtained in randomized studies.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05450367
Study type Observational
Source Assistance Publique - Hôpitaux de Paris
Contact Jeremie Zerbit, PharmD
Phone 00 33 1 58 41 41 41
Email jeremie.zerbit@aphp.fr
Status Recruiting
Phase
Start date August 1, 2017
Completion date July 15, 2022

See also
  Status Clinical Trial Phase
Active, not recruiting NCT04188678 - Resiliency in Older Adults Undergoing Bone Marrow Transplant N/A
Not yet recruiting NCT06455592 - Effect of APA on Sleep Quality in Children With Cancer From 5 to 16 Years N/A
Completed NCT03654404 - A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients N/A
Recruiting NCT06116032 - Immune Profiling for Cancer Immunotherapy Response
Recruiting NCT04955938 - A Study of Fedratinib With IDH Inhibition in Advanced-Phase, IDH-Mutated Ph-Negative Myeloproliferative Neoplasms Phase 1
Recruiting NCT06119685 - IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers Phase 1/Phase 2
Not yet recruiting NCT05391490 - Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies Phase 1
Not yet recruiting NCT06469307 - Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)
Recruiting NCT05709522 - Neurocognitive and Psychosocial Outcomes Among Pediatric Brain Tumor and Blood Cancer Patients
Completed NCT00186225 - Stem Cell Transplant From Matched Unrelated or Partially Matched Related Donors N/A
Active, not recruiting NCT05147311 - Positive Psychology Intervention In HSCT N/A
Recruiting NCT04372524 - Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study
Completed NCT01957579 - A Phase 1, Dose-escalation Study of MEDI-551 in Japanese Adult Patients With Relapsed or Refractory Advanced B-cell Malignancies Phase 1
Completed NCT00185640 - Allogeneic Transplantation Using Total Lymphoid Irradiation (TLI) and Anti-Thymocyte Globulin (ATG) for Older Patients With Hematologic Malignancies Phase 2
Withdrawn NCT04390542 - Intervention for Caregivers of Patients Undergoing HSCT or CAR T-cell Therapy N/A
Completed NCT04419623 - A Study of TL-895 With Standard Available Treatment Versus Standard Available Treatment for the Treatment of COVID-19 in Patients With Cancer Phase 1
Recruiting NCT04806295 - The Leukemia and Lymphoma Society (LLS) National Research Registry
Recruiting NCT05873205 - Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation Phase 2
Completed NCT00962494 - Cancer: Thriving and Surviving Online Workshop and Study for Cancer Survivors Phase 2
Completed NCT00185796 - TLI & ATG for Non-Myeloablative Allogeneic Transplantation for MDS and MPD Phase 2